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Catalog Number:
37606
CAS Number:
141396-28-3
Argatroban monohidrato
Purity:
≥ 99 % (HPLC)
Synonym(s):
Ácido (2 R ,4 R )-1-[(2 S )-5-[(Aminoiminometil)amino]-1-oxo-2-[[(1,2,3,4-tetrahidro-3-metil-8-quinolinil)sulfonil]amino]pentil]-4-metil-2-piperidinacarboxílico monohidrato, Monohidrato de argipidina
Documents
$318.68 /25 mg
Tamaño
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Product Information

Argatroban monohydrate is a potent synthetic anticoagulant that plays a crucial role in the management of thromboembolic disorders. This compound is particularly valuable in clinical settings for patients who are at risk of thrombosis, especially those with heparin-induced thrombocytopenia (HIT). Its mechanism of action involves direct inhibition of thrombin, making it an essential alternative to traditional anticoagulants. Researchers and healthcare professionals appreciate Argatroban monohydrate for its rapid onset of action and predictable pharmacokinetics, which facilitate effective dosing and monitoring.

In addition to its therapeutic applications, Argatroban monohydrate is also utilized in various research settings, particularly in studies focused on coagulation and cardiovascular health. Its unique properties allow for detailed investigations into thrombin's role in hemostasis and thrombosis, providing insights that can lead to the development of new anticoagulant therapies. With its established efficacy and safety profile, Argatroban monohydrate stands out as a reliable choice for both clinical and research applications, offering significant benefits over other anticoagulants in specific patient populations.

Synonyms
Ácido (2 R ,4 R )-1-[(2 S )-5-[(Aminoiminometil)amino]-1-oxo-2-[[(1,2,3,4-tetrahidro-3-metil-8-quinolinil)sulfonil]amino]pentil]-4-metil-2-piperidinacarboxílico monohidrato, Monohidrato de argipidina
CAS Number
141396-28-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C23H36N6O5S · H2O
Molecular Weight
526.66
MDL Number
MFCD00895735
PubChem ID
18431974
Melting Point
180 °C (descenso)
Appearance
Polvo blanco a casi blanco a cristal.
Optical Rotation
[a]20D = 160 - 170 ° (C = 0,8 en MeOH) (calculado sobre sustancia anh.)
Conditions
Conservar entre 2 y 8 °C.
General Information
Synonyms
Ácido (2 R ,4 R )-1-[(2 S )-5-[(Aminoiminometil)amino]-1-oxo-2-[[(1,2,3,4-tetrahidro-3-metil-8-quinolinil)sulfonil]amino]pentil]-4-metil-2-piperidinacarboxílico monohidrato, Monohidrato de argipidina
CAS Number
141396-28-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C23H36N6O5S · H2O
Molecular Weight
526.66
MDL Number
MFCD00895735
PubChem ID
18431974
Melting Point
180 °C (descenso)
Appearance
Polvo blanco a casi blanco a cristal.
Optical Rotation
[a]20D = 160 - 170 ° (C = 0,8 en MeOH) (calculado sobre sustancia anh.)
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Argatroban monohydrate is widely utilized in research focused on:

  • Anticoagulant Therapy: It is primarily used as an anticoagulant in patients with heparin-induced thrombocytopenia (HIT), providing a crucial alternative for those who cannot use heparin.
  • Cardiovascular Research: Researchers utilize it to study its effects on blood coagulation and cardiovascular health, helping to develop better treatments for heart diseases.
  • Pharmaceutical Development: The compound plays a significant role in the formulation of new anticoagulant medications, aiding pharmaceutical companies in creating safer and more effective drugs.
  • Clinical Trials: It is frequently involved in clinical trials aimed at evaluating its efficacy and safety in various patient populations, contributing to evidence-based medicine.
  • Laboratory Studies: In laboratory settings, it is used to investigate the mechanisms of blood clotting and the effects of anticoagulants, providing insights that can lead to innovative therapeutic strategies.

Citas