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Catalog Number:
22101
CAS Number:
20350-15-6
Brefeldina A
Purity:
≥ 99 % (HPLC)
Synonym(s):
ácido g,4-dihidroxi-2-(6-hidroxi-1-heptenil)-4-ciclopentanecrotónico l-lactona, Ascotoxin
Temperature Sensitive
Documents
$70.50 /10 mg
Tamaño
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Product Information

Brefeldin A is a potent fungal metabolite renowned for its ability to disrupt protein transport within cells, making it an invaluable tool in cellular biology and pharmacological research. This compound has gained significant attention for its role in studying the Golgi apparatus and endoplasmic reticulum functions, as well as its potential applications in cancer therapy and antiviral research. Researchers utilize Brefeldin A to elucidate mechanisms of intracellular trafficking and to investigate the effects of protein misfolding, which is crucial in understanding various diseases.

In addition to its fundamental research applications, Brefeldin A has shown promise in therapeutic contexts, particularly in the modulation of immune responses and the inhibition of viral replication. Its unique ability to induce apoptosis in certain cancer cell lines positions it as a candidate for further exploration in oncology. With its diverse applications and significant impact on cellular studies, Brefeldin A remains a critical compound for researchers aiming to advance our understanding of cellular processes and develop innovative therapeutic strategies.

Synonyms
ácido g,4-dihidroxi-2-(6-hidroxi-1-heptenil)-4-ciclopentanecrotónico l-lactona, Ascotoxin
CAS Number
20350-15-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C16H24O4
Molecular Weight
280.36
MDL Number
MFCD12913297
PubChem ID
2430
Melting Point
204 - 207 °C
Appearance
Polvo blanco
Conditions
Conservar a -10 °C
General Information
Synonyms
ácido g,4-dihidroxi-2-(6-hidroxi-1-heptenil)-4-ciclopentanecrotónico l-lactona, Ascotoxin
CAS Number
20350-15-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C16H24O4
Molecular Weight
280.36
MDL Number
MFCD12913297
PubChem ID
2430
Melting Point
204 - 207 °C
Appearance
Polvo blanco
Conditions
Conservar a -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Brefeldin A is widely utilized in research focused on:

  • Cell Biology: It is commonly used to study the secretory pathway in cells, helping researchers understand how proteins are processed and transported.
  • Drug Development: Its ability to disrupt Golgi function makes it a valuable tool in the development of new therapeutic agents targeting cellular transport mechanisms.
  • Neuroscience: Researchers leverage Brefeldin A to investigate synaptic plasticity and neuronal signaling, providing insights into neurodegenerative diseases.
  • Plant Biology: It is applied in studies of plant cell signaling and growth, aiding in the exploration of plant responses to environmental stressors.
  • Viral Research: The compound is used to examine the mechanisms of viral replication and assembly, contributing to the development of antiviral strategies.

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