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Clorhidrato de fenoxibenzamina
Phenoxybenzamine hydrochloride is widely utilized in research focused on:
- Medical Treatment of Pheochromocytoma: This compound is primarily used to manage symptoms associated with pheochromocytoma, a rare tumor of the adrenal gland that can cause hypertension. By blocking the effects of catecholamines, it helps stabilize blood pressure in patients.
- Research in Pharmacology: It serves as a valuable tool in pharmacological studies to understand adrenergic receptor interactions and the mechanisms of action of other antihypertensive drugs, providing insights into cardiovascular health.
- Preoperative Preparation: In surgical settings, it is administered to patients with pheochromocytoma to prevent hypertensive crises during surgery, ensuring safer surgical outcomes.
- Neuroscience Studies: Researchers use phenoxybenzamine to explore its effects on neurotransmitter systems, aiding in the understanding of conditions like depression and anxiety, where adrenergic systems are implicated.
- Comparative Studies: It is often compared with other irreversible alpha-adrenergic antagonists in clinical trials, helping to establish its efficacy and safety profile relative to similar compounds.
General Information
Properties
Safety and Regulations
Applications
Phenoxybenzamine hydrochloride is widely utilized in research focused on:
- Medical Treatment of Pheochromocytoma: This compound is primarily used to manage symptoms associated with pheochromocytoma, a rare tumor of the adrenal gland that can cause hypertension. By blocking the effects of catecholamines, it helps stabilize blood pressure in patients.
- Research in Pharmacology: It serves as a valuable tool in pharmacological studies to understand adrenergic receptor interactions and the mechanisms of action of other antihypertensive drugs, providing insights into cardiovascular health.
- Preoperative Preparation: In surgical settings, it is administered to patients with pheochromocytoma to prevent hypertensive crises during surgery, ensuring safer surgical outcomes.
- Neuroscience Studies: Researchers use phenoxybenzamine to explore its effects on neurotransmitter systems, aiding in the understanding of conditions like depression and anxiety, where adrenergic systems are implicated.
- Comparative Studies: It is often compared with other irreversible alpha-adrenergic antagonists in clinical trials, helping to establish its efficacy and safety profile relative to similar compounds.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Número de catálogo
Número de lote/lote
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
Número de catálogo
Número de lote/lote
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Número de catálogo
Número de lote/lote
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.