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Catalog Number:
16861
CAS Number:
1217808-42-8
Fmoc-2-(Boc-aminomethyl)phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Phe(2-CH2NHBoc)-OH, Fmoc-2-(Boc-aminomethyl)-L-Phe-OH, Fmoc-Phe(2-CH2NHBoc)-OH
Documents
$65.00 /100MG
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Product Information

Fmoc-2-(Boc-aminomethyl)phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. The Boc (tert-butyloxycarbonyl) group further enhances its stability and reactivity, making it an ideal choice for researchers looking to streamline their synthesis processes.

In practical applications, Fmoc-2-(Boc-aminomethyl)phenylalanine is particularly valuable in the production of complex peptides and proteins, which are crucial in pharmaceutical research and development. Its unique structure allows for improved solubility and compatibility with various coupling reagents, facilitating efficient synthesis. This compound is also used in the development of peptide-based therapeutics, where precise control over amino acid sequences is paramount. Researchers appreciate its reliability and effectiveness, making it a preferred choice in both academic and industrial settings.

Synonyms
Fmoc-L-Phe(2-CH2NHBoc)-OH, Fmoc-2-(Boc-aminomethyl)-L-Phe-OH, Fmoc-Phe(2-CH2NHBoc)-OH
CAS Number
1217808-42-8
Purity
≥ 99% (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659138
PubChem ID
53398426
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Phe(2-CH2NHBoc)-OH, Fmoc-2-(Boc-aminomethyl)-L-Phe-OH, Fmoc-Phe(2-CH2NHBoc)-OH
CAS Number
1217808-42-8
Purity
≥ 99% (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659138
PubChem ID
53398426
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-(Boc-aminomethyl)phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.
  • Drug Development: It plays a significant role in pharmaceutical research, where it is used to develop peptide-based drugs, enhancing the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The compound is valuable in bioconjugation applications, facilitating the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Cancer Therapy: Its derivatives are explored in cancer research, where they are used to design peptide ligands that can selectively target cancer cells, improving treatment outcomes.
  • Protein Engineering: This chemical is employed in protein engineering to modify protein structures, aiding in the development of novel proteins with enhanced stability and functionality.

Citations