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Catalog Number:
37581
CAS Number:
1744-22-5
Riluzole
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
2-Amino-6-(trifluoromethoxy)benzothiazole
Hazmat
Documents
$72.31 /5G
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Product Information

Riluzole is a potent pharmaceutical compound primarily recognized for its role in the treatment of amyotrophic lateral sclerosis (ALS). This innovative drug works by modulating glutamate release, thereby protecting motor neurons from excitotoxicity, which is a key factor in the progression of ALS. Its unique trifluoromethoxy group enhances its bioavailability and efficacy, making it a valuable asset in neurological research and therapeutic applications.

In addition to its primary use in ALS, Riluzole has shown promise in various other neurological disorders, including certain types of epilepsy and mood disorders, highlighting its versatility. Researchers and healthcare professionals appreciate Riluzole not only for its therapeutic benefits but also for its potential in advancing studies related to neuroprotection and neurodegenerative diseases. Its established safety profile and effectiveness make it a preferred choice in both clinical and research settings, paving the way for further exploration of its capabilities in treating complex neurological conditions.

Synonyms
2-Amino-6-(trifluoromethoxy)benzothiazole
CAS Number
1744-22-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C8H5F3N2OS
Molecular Weight
234.2
MDL Number
MFCD00210213
PubChem ID
5070
Melting Point
116 - 120 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Amino-6-(trifluoromethoxy)benzothiazole
CAS Number
1744-22-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C8H5F3N2OS
Molecular Weight
234.2
MDL Number
MFCD00210213
PubChem ID
5070
Melting Point
116 - 120 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Riluzole is widely utilized in research focused on

  • Treatment of Amyotrophic Lateral Sclerosis (ALS): Riluzole is primarily used in the medical field to slow the progression of ALS, providing patients with improved quality of life and extended survival.
  • Neuroprotective Research: Researchers explore Riluzole's neuroprotective properties in various neurological disorders, making it a valuable compound in studies aimed at understanding and treating conditions like multiple sclerosis and Huntington's disease.
  • Pharmaceutical Development: The compound serves as a template for developing new drugs targeting glutamate toxicity, which is implicated in several neurodegenerative diseases, enhancing the drug discovery process.
  • Veterinary Medicine: Riluzole is also being investigated for its potential applications in treating neurological disorders in animals, particularly in dogs with similar conditions to ALS.
  • Research on Depression and Anxiety: Some studies are examining Riluzole's effects on mood disorders, providing insights into its potential as an alternative treatment for depression and anxiety, thus broadening its therapeutic scope.

Citations