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Catalog Number:
37587
CAS Number:
121268-17-5
Alendronate sodium trihydrate
Grade:
USP
Purity:
98 - 102% (Assay, on dried basis)
Synonym(s):
Alendronic acid monosodium salt trihydrate, Monosodium (4-Amino-1-hydroxy-1-phosphonobutyl)phosphonate trihydrate
Temperature Sensitive
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$22.43 /5G
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Product Information

Alendronate sodium trihydrate is a potent bisphosphonate compound primarily utilized in the treatment of osteoporosis and other bone-related disorders. This compound works by inhibiting osteoclast-mediated bone resorption, thereby enhancing bone density and strength. Its unique ability to bind to hydroxyapatite in bone tissue makes it particularly effective in preventing fractures in postmenopausal women and individuals with glucocorticoid-induced osteoporosis. Researchers and healthcare professionals appreciate its stability and solubility, which facilitate its formulation into various dosage forms, including oral tablets and injectable solutions.

In addition to its therapeutic applications, Alendronate sodium trihydrate is also being explored for its potential use in veterinary medicine and in the treatment of Paget's disease. Its effectiveness in reducing bone pain and improving mobility in affected patients highlights its versatility. With a strong safety profile and proven efficacy, this compound continues to be a valuable asset in both clinical and research settings, offering significant benefits to patients and healthcare providers alike.

Synonyms
Alendronic acid monosodium salt trihydrate, Monosodium (4-Amino-1-hydroxy-1-phosphonobutyl)phosphonate trihydrate
CAS Number
121268-17-5
Purity
98 - 102% (Assay, on dried basis)
Grade
USP
Molecular Formula
C4H12NNaO7P2·3H2O
Molecular Weight
325.13
MDL Number
MFCD01748233
PubChem ID
60736
Appearance
White crystalline powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Alendronic acid monosodium salt trihydrate, Monosodium (4-Amino-1-hydroxy-1-phosphonobutyl)phosphonate trihydrate
CAS Number
121268-17-5
Purity
98 - 102% (Assay, on dried basis)
Grade
USP
Molecular Formula
C4H12NNaO7P2·3H2O
Molecular Weight
325.13
MDL Number
MFCD01748233
PubChem ID
60736
Appearance
White crystalline powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Alendronate sodium trihydrate is widely utilized in research focused on:

  • Osteoporosis Treatment: This compound is primarily used in the treatment of osteoporosis, helping to strengthen bones and reduce the risk of fractures in postmenopausal women and individuals on long-term corticosteroid therapy.
  • Bone Metabolism Studies: Researchers employ it to study bone metabolism and the effects of bisphosphonates on bone density, providing valuable insights for developing new therapies.
  • Pharmaceutical Formulations: It is incorporated into various pharmaceutical formulations, enhancing the bioavailability of medications aimed at improving bone health.
  • Veterinary Medicine: Alendronate sodium trihydrate is also applied in veterinary medicine for treating bone disorders in animals, showcasing its versatility beyond human health.
  • Comparative Effectiveness Research: The compound is used in comparative studies to evaluate the effectiveness of different osteoporosis treatments, helping healthcare providers make informed decisions.

Citations