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Catalog Number:
37597
CAS Number:
95233-18-4
Atovaquone
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione, Mepron
Temperature Sensitive
Documents
$149.62 /200MG
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Product Information

Atovaquone is a potent antiprotozoal agent primarily used in the treatment of Pneumocystis pneumonia (PCP) and certain forms of malaria. This compound exhibits a unique mechanism of action by selectively inhibiting mitochondrial electron transport in protozoa, making it an essential therapeutic option for immunocompromised patients. Its lipophilic nature enhances its bioavailability, allowing for effective absorption and distribution within the body.

In addition to its primary applications in infectious disease treatment, Atovaquone has shown promise in research settings, particularly in the study of mitochondrial function and drug resistance mechanisms. Its ability to target specific cellular pathways makes it a valuable tool for researchers exploring new therapeutic strategies. With its favorable safety profile and efficacy, Atovaquone stands out as a critical compound in both clinical and research environments, providing significant benefits in the fight against parasitic infections.

Synonyms
trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione, Mepron
CAS Number
95233-18-4
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C22H19ClO3
Molecular Weight
366.84
MDL Number
MFCD00889188
PubChem ID
74989
Melting Point
221 - 225 °C
Appearance
Light yellow to brown powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione, Mepron
CAS Number
95233-18-4
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C22H19ClO3
Molecular Weight
366.84
MDL Number
MFCD00889188
PubChem ID
74989
Melting Point
221 - 225 °C
Appearance
Light yellow to brown powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Atovaquone is widely utilized in research focused on

  • Antimicrobial Treatments: Primarily used in the treatment of malaria and certain types of pneumonia, Atovaquone effectively targets the parasites responsible for these diseases, making it essential in tropical medicine.
  • Research in Infectious Diseases: Its unique mechanism of action allows researchers to study the pathways of parasitic infections, aiding in the development of new therapeutic strategies.
  • Combination Therapy: Often used in conjunction with other medications, Atovaquone enhances treatment efficacy for patients with complex infections, providing a more comprehensive approach to patient care.
  • Veterinary Medicine: This compound is also applied in veterinary settings to treat infections in animals, showcasing its versatility beyond human health.
  • Pharmaceutical Development: Its role in drug formulation and delivery systems allows for improved bioavailability and patient compliance, making it a valuable component in pharmaceutical research.

Citations