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Catalog Number:
37631
CAS Number:
86357-14-4
N-Acetyl-di-O-acetylganciclovir
Purity:
≥ 98% (HPLC)
Synonym(s):
N-[9-[[2-(Acetyloxy)-1-[(acetyloxy)methyl]ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]acetamide, Triacetylganciclovir
Documents
$86.23 /1G
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Product Information

N-Acetyl-di-O-acetylganciclovir is a potent antiviral compound that has garnered attention for its efficacy in treating viral infections, particularly those caused by cytomegalovirus (CMV). This compound is a derivative of ganciclovir, modified to enhance its pharmacological properties, making it a valuable asset in antiviral therapy. Its unique structure allows for improved bioavailability and stability, which are critical factors in the development of effective antiviral medications.

Researchers and pharmaceutical professionals can leverage N-Acetyl-di-O-acetylganciclovir in various applications, including the formulation of antiviral drugs aimed at treating CMV infections in immunocompromised patients, such as those undergoing organ transplantation or chemotherapy. Its ability to inhibit viral replication makes it a crucial component in the ongoing fight against viral diseases. Additionally, the compound's favorable safety profile and enhanced potency compared to traditional ganciclovir derivatives position it as a promising candidate for further research and development in antiviral therapies.

Synonyms
N-[9-[[2-(Acetyloxy)-1-[(acetyloxy)methyl]ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]acetamide, Triacetylganciclovir
CAS Number
86357-14-4
Purity
≥ 98% (HPLC)
Molecular Formula
C15H19N5O7
Molecular Weight
381.35
MDL Number
MFCD08457700
PubChem ID
135427290
Melting Point
172 - 176 °C
Appearance
White to orange to green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-[9-[[2-(Acetyloxy)-1-[(acetyloxy)methyl]ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]acetamide, Triacetylganciclovir
CAS Number
86357-14-4
Purity
≥ 98% (HPLC)
Molecular Formula
C15H19N5O7
Molecular Weight
381.35
MDL Number
MFCD08457700
PubChem ID
135427290
Melting Point
172 - 176 °C
Appearance
White to orange to green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Acetyl-di-O-acetylganciclovir is widely utilized in research focused on:

  • Antiviral Drug Development: This compound serves as a prodrug for ganciclovir, enhancing its bioavailability and effectiveness against viral infections, particularly cytomegalovirus (CMV).
  • Pharmaceutical Formulations: It is used in the formulation of antiviral medications, allowing for improved stability and controlled release, which is crucial for patient compliance.
  • Research on Drug Resistance: Scientists study this compound to understand mechanisms of resistance in viral pathogens, helping to develop more effective treatments.
  • Biochemical Studies: It is employed in laboratory experiments to investigate cellular uptake and metabolism of antiviral agents, providing insights into their pharmacokinetics.
  • Clinical Trials: The compound is often included in clinical research to evaluate new therapeutic strategies for treating viral infections, contributing to advancements in medical science.

Citations