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Catalog Number:
47027
Fmoc-D-Phe(3-COOtBu)-OH
Purity:
≥ 99.5% (Chiral HPLC)
Documents
$210.00 /100MG
Pack Size Availability Price
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Product Information

Fmoc-D-Phe(3-COOtBu)-OH is a highly versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, known for its protective Fmoc (9-fluorenylmethoxycarbonyl) group, facilitates the efficient assembly of peptides by providing a stable and easily removable protecting group. Its unique structure, featuring a t-butyl ester at the 3-position, enhances solubility and stability, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry.

In practical applications, Fmoc-D-Phe(3-COOtBu)-OH is particularly valuable in solid-phase peptide synthesis (SPPS), where it serves as a building block for creating complex peptides and proteins. Its ability to streamline the synthesis process while maintaining high purity levels is a significant advantage over other amino acid derivatives. Researchers and industry professionals can leverage this compound to develop novel therapeutics, optimize drug formulations, and explore new biochemical pathways, ultimately contributing to advancements in pharmaceutical research and development.

Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.54
Appearance
White powder
Optical Rotation
[ॅ]D20 = 25 +/- 1 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.54
Appearance
White powder
Optical Rotation
[ॅ]D20 = 25 +/- 1 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Phe(3-COOtBu)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, helping researchers create more effective and targeted drug candidates.
  • Bioconjugation: The compound is used in bioconjugation strategies, enabling the attachment of peptides to various biomolecules, which is essential in creating targeted delivery systems for drugs.
  • Research in Neuroscience: It is applied in the synthesis of neuropeptides, facilitating studies on their role in neurological functions and potential treatments for neurodegenerative diseases.
  • Analytical Chemistry: The compound aids in the development of analytical methods for peptide analysis, improving the accuracy and reliability of results in various research settings.

Citations