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Catalog Number:
15114
CAS Number:
478183-67-4
Fmoc-3-yodo-D-fenilalanina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Phe(3-I)-OH, Fmoc- m -yodo-D-Phe-OH, (Ácido R -2-Fmoc-2-amino-3-(3-yodofenil)propiónico
Documents
$134.70 /1G
Tamaño
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Product Information

Fmoc-3-iodo-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of an iodine atom, enhances its utility in various applications, including medicinal chemistry and bioconjugation. Researchers appreciate its ability to facilitate the incorporation of iodine into peptides, which can be crucial for radiolabeling and imaging studies.

In addition to its role in peptide synthesis, Fmoc-3-iodo-D-phenylalanine is also valuable in the development of novel therapeutics, particularly in the field of cancer research. The compound's properties allow for the exploration of new drug candidates that can target specific biological pathways. Its stability and compatibility with various coupling reagents make it an excellent choice for researchers looking to streamline their synthesis processes while achieving high yields. With its broad range of applications, Fmoc-3-iodo-D-phenylalanine stands out as a key building block for innovative research and development in the pharmaceutical industry.

Synonyms
Fmoc-D-Phe(3-I)-OH, Fmoc- m -yodo-D-Phe-OH, (Ácido R -2-Fmoc-2-amino-3-(3-yodofenil)propiónico
CAS Number
478183-67-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 20 INOX 4
Molecular Weight
513.4
MDL Number
MFCD03840402
PubChem ID
53427493
Melting Point
147-152 °C
Appearance
Polvo blanquecino
Optical Rotation
[a] D 25 = +19 ± 2º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-D-Phe(3-I)-OH, Fmoc- m -yodo-D-Phe-OH, (Ácido R -2-Fmoc-2-amino-3-(3-yodofenil)propiónico
CAS Number
478183-67-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 20 INOX 4
Molecular Weight
513.4
MDL Number
MFCD03840402
PubChem ID
53427493
Melting Point
147-152 °C
Appearance
Polvo blanquecino
Optical Rotation
[a] D 25 = +19 ± 2º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-iodo-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptides with specific sequences.
  • Drug Development: Its unique structure makes it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific proteins or enzymes.
  • Bioconjugation: The iodine atom can be used for labeling or modifying biomolecules, making it useful in bioconjugation techniques for imaging or therapeutic applications.
  • Research on Protein Interactions: This compound aids in studying protein-protein interactions, providing insights into biological processes and potential therapeutic targets.
  • Customizable Modifications: The Fmoc protecting group allows for easy modifications during synthesis, offering flexibility in designing peptides with desired properties.

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