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Catalog Number:
37643
CAS Number:
90357-06-5
Bicalutamide
Purity:
≥ 98 % (HPLC)
Synonym(s):
N- [4-cyano-3-(trifluorométhyl)phényl]-3-[(4-fluorophényl)sulfonyl]-2-hydroxy-2-méthylpropionamide
Documents
$82.02 /200 mg
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Product Information

Bicalutamide is a potent non-steroidal anti-androgen widely recognized for its application in the treatment of prostate cancer. This compound functions by inhibiting the action of androgens, such as testosterone, thereby effectively slowing the growth of hormone-sensitive tumors. Its unique structure, featuring a trifluoromethyl group and a sulfonamide moiety, enhances its binding affinity to androgen receptors, making it a preferred choice in therapeutic regimens. Bicalutamide is often utilized in combination with other treatments, such as luteinizing hormone-releasing hormone (LHRH) agonists, to maximize efficacy in managing advanced prostate cancer.

In addition to its primary use in oncology, Bicalutamide has shown potential in research settings for exploring androgen-related conditions and hormone modulation. Its favorable pharmacokinetic profile allows for oral administration, providing convenience for patients. Researchers and healthcare professionals appreciate Bicalutamide for its ability to improve patient outcomes while minimizing side effects compared to traditional therapies. As the demand for effective cancer treatments continues to grow, Bicalutamide remains a critical component in the fight against prostate cancer, offering hope and improved quality of life for patients.

Synonyms
N- [4-cyano-3-(trifluorométhyl)phényl]-3-[(4-fluorophényl)sulfonyl]-2-hydroxy-2-méthylpropionamide
CAS Number
90357-06-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C18H14F4N2O4S
Molecular Weight
430.37
MDL Number
MFCD00869971
PubChem ID
2375
Melting Point
194 - 198 °C
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
N- [4-cyano-3-(trifluorométhyl)phényl]-3-[(4-fluorophényl)sulfonyl]-2-hydroxy-2-méthylpropionamide
CAS Number
90357-06-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C18H14F4N2O4S
Molecular Weight
430.37
MDL Number
MFCD00869971
PubChem ID
2375
Melting Point
194 - 198 °C
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Bicalutamide is widely utilized in research focused on:

  • Prostate Cancer Treatment: Primarily used as an anti-androgen medication, it helps in managing advanced prostate cancer by inhibiting testosterone effects, providing a critical option for patients.
  • Hormone Therapy Studies: Bicalutamide serves as a key compound in studies exploring hormone therapy's efficacy, allowing researchers to understand its role in hormone-dependent cancers.
  • Combination Therapy Research: It is often investigated in combination with other treatments, such as LHRH agonists, to enhance therapeutic outcomes and reduce side effects in cancer management.
  • Pharmacokinetics and Drug Interaction Studies: Researchers utilize it to study how the drug interacts with other medications, helping to optimize treatment regimens and improve patient safety.
  • Development of New Anti-Cancer Drugs: Its unique properties inspire the design of novel compounds, offering potential advancements in cancer treatment strategies.

Citations