🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
07399
CAS Number:
205526-31-4
Fmoc-3,4,5-trifluoro-D-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Phe(3,4,5-trifluoro)-OH
Documents
$65.40 /250 mg
Taille
Request Bulk Quote
Product Information

Fmoc-3,4,5-trifluoro-D-phenylalanine is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique trifluorophenyl group, enhancing its hydrophobic properties and making it an excellent choice for researchers focusing on the design of potent bioactive peptides. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into solid-phase peptide synthesis, facilitating the production of complex peptides with improved stability and bioactivity.

This compound is particularly valuable in the pharmaceutical industry, where it can be utilized to develop peptide-based therapeutics, including those targeting specific receptors or enzymes. Its unique properties enable researchers to explore new avenues in drug discovery, particularly in the development of fluorinated compounds that exhibit enhanced metabolic stability. Fmoc-3,4,5-trifluoro-D-phenylalanine stands out among similar compounds due to its ability to improve the efficacy of peptide drugs while maintaining a favorable safety profile, making it an essential tool for professionals in medicinal chemistry and biochemistry.

Synonyms
Fmoc-D-Phe(3,4,5-trifluoro)-OH
CAS Number
205526-31-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 18 F 3 NON 4
Molecular Weight
441.41
MDL Number
MFCD00797584
PubChem ID
53395418
Melting Point
166-172 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +42 ± 3º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(3,4,5-trifluoro)-OH
CAS Number
205526-31-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 18 F 3 NON 4
Molecular Weight
441.41
MDL Number
MFCD00797584
PubChem ID
53395418
Melting Point
166-172 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +42 ± 3º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3,4,5-trifluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of fluorinated amino acids that can enhance the stability and bioactivity of the resulting peptides.
  • Drug Development: Its unique trifluoromethyl group can improve the pharmacokinetic properties of drug candidates, making it valuable in medicinal chemistry for designing more effective therapeutics.
  • Bioconjugation: The chemical's functional groups facilitate bioconjugation processes, enabling researchers to attach biomolecules to peptides for applications in targeted drug delivery and diagnostics.
  • Fluorine-Containing Compounds: The incorporation of fluorine can alter the lipophilicity and metabolic stability of compounds, making it useful in the development of new materials and pharmaceuticals with improved performance.
  • Research in Neuroscience: Its application in the synthesis of peptide ligands for receptors involved in neurological pathways can help in understanding and treating neurodegenerative diseases.

Citations