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Catalog Number:
15936
CAS Number:
959582-85-5
Boc- R) -γ-(3-trifluorométhylbenzyl)-L-proline
Purity:
≥ 98 % (HPLC)
Documents
$60.00 /25 mg
Taille
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Product Information

Boc-(R)-g-(3-trifluoromethylbenzyl)-L-proline is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its unique trifluoromethyl group, which enhances lipophilicity and metabolic stability, making it an excellent choice for researchers focused on developing novel pharmaceuticals. Its Boc (tert-butyloxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptides with high purity and yield.

In the pharmaceutical industry, Boc-(R)-g-(3-trifluoromethylbenzyl)-L-proline is utilized in the design of peptide-based therapeutics, particularly in the development of inhibitors and modulators for various biological targets. Its ability to improve the pharmacokinetic properties of peptide drugs makes it a valuable asset in medicinal chemistry. Researchers can leverage this compound to create more effective treatments with reduced side effects, thus enhancing the overall efficacy of drug candidates.

CAS Number
959582-85-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C 18 H 22 F 3 NON 4
Molecular Weight
373.37
MDL Number
MFCD06659428
PubChem ID
53398265
Melting Point
140-146 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 25 = -58 ± 2º (C = 1 dans CH 2 Cl 2 )
Conditions
Conserver à 0-8 °C
General Information
CAS Number
959582-85-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C 18 H 22 F 3 NON 4
Molecular Weight
373.37
MDL Number
MFCD06659428
PubChem ID
53398265
Melting Point
140-146 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 25 = -58 ± 2º (C = 1 dans CH 2 Cl 2 )
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-(R)-g-(3-trifluoromethylbenzyl)-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating specific sequences that are crucial for drug development.
  • Medicinal Chemistry: It is employed in the design of novel pharmaceuticals, especially those targeting neurological disorders, due to its ability to enhance bioactivity and selectivity.
  • Bioconjugation: The chemical is used in bioconjugation techniques, allowing researchers to attach biomolecules to drugs, improving their delivery and efficacy in therapeutic applications.
  • Research on Protein Interactions: It aids in studying protein-ligand interactions, providing insights into molecular mechanisms that can lead to the development of new therapeutic strategies.
  • Fluorinated Compound Development: The trifluoromethyl group contributes to the stability and lipophilicity of compounds, making it valuable in the development of fluorinated drugs that exhibit enhanced pharmacokinetic properties.

Citations