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Catalog Number:
19758
CAS Number:
864771-44-8
Ester pinacolique de l'acide 1-Boc-1 H -indazole-5-boronique
Purity:
≥ 95%
Synonym(s):
tert -butyl5-(4,4,5,5-tétraméthyl-1,3,2-dioxaborolan-2-yl)-1 H -indazole-1-carboxylate
Documents
$65.40 /100 mg
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Product Information

1-Boc-1H-indazole-5-boronic acid pinacol ester is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative features a tert-butyl protecting group, which enhances its stability and solubility, making it an excellent choice for various chemical reactions. Its unique structure allows for efficient coupling reactions, particularly in the formation of complex organic molecules, including pharmaceuticals and agrochemicals. Researchers appreciate its role in Suzuki-Miyaura cross-coupling reactions, which are pivotal in constructing carbon-carbon bonds, thus facilitating the development of novel compounds with potential therapeutic applications.

This compound's pinacol ester form further contributes to its utility, providing enhanced reactivity and compatibility with a range of functional groups. Its application extends to the synthesis of biologically active molecules, where it serves as a key intermediate. The ability to easily manipulate its structure allows chemists to explore diverse synthetic pathways, making 1-Boc-1H-indazole-5-boronic acid pinacol ester an essential tool in the arsenal of researchers and industry professionals focused on drug discovery and development.

Synonyms
tert -butyl5-(4,4,5,5-tétraméthyl-1,3,2-dioxaborolan-2-yl)-1 H -indazole-1-carboxylate
CAS Number
864771-44-8
Purity
≥ 95%
Molecular Formula
C18H25BN2O4
Molecular Weight
344.22
MDL Number
MFCD08437629
PubChem ID
18525862
Appearance
Poudre ou solide beige à brunâtre
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
tert -butyl5-(4,4,5,5-tétraméthyl-1,3,2-dioxaborolan-2-yl)-1 H -indazole-1-carboxylate
CAS Number
864771-44-8
Purity
≥ 95%
Molecular Formula
C18H25BN2O4
Molecular Weight
344.22
MDL Number
MFCD08437629
PubChem ID
18525862
Appearance
Poudre ou solide beige à brunâtre
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

1-Boc-1H-indazole-5-boronic acid pinacol ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of new drugs targeting cancer and neurological disorders.
  • Organic Synthesis: It is employed in cross-coupling reactions, enabling the formation of complex organic molecules, which is essential in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in creating advanced materials, such as polymers and nanomaterials, which have applications in electronics and coatings.
  • Bioconjugation: It facilitates the attachment of biomolecules to surfaces or other molecules, enhancing drug delivery systems and diagnostic tools in medical research.
  • Research in Catalysis: This boronic acid derivative is valuable in catalytic processes, improving reaction efficiency and selectivity in synthetic chemistry.

Citations