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Catalog Number:
30492
CAS Number:
1248587-10-1
Acide N α -Fmoc-N β -triméthylsilyléthoxycarbonyl-L-diaminopropionique
Purity:
≥ 98 % (dosage par titration, HPLC)
Synonym(s):
Fmoc-L-Dap(Teoc)-OH
Documents
$83.32 /100 mg
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Product Information

Na-Fmoc-Nb-trimethylsilylethoxycarbonyl-L-diaminopropionic acid is a versatile building block in peptide synthesis, particularly valued for its protective group functionalities. This compound features a fluorenylmethoxycarbonyl (Fmoc) group, which is widely used in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal. The presence of the trimethylsilylethoxycarbonyl (TMS-OC) moiety enhances its solubility and reactivity, making it an excellent choice for complex peptide sequences. Researchers and industry professionals can leverage this compound to streamline the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.

This compound is particularly beneficial in the synthesis of peptides that require multiple protection strategies, allowing for selective deprotection and functionalization. Its unique structure enables efficient coupling reactions, which can significantly reduce synthesis time and improve yields compared to traditional methods. As a result, Na-Fmoc-Nb-trimethylsilylethoxycarbonyl-L-diaminopropionic acid is an essential tool for chemists looking to enhance their peptide synthesis workflows and achieve high-purity products.

Synonyms
Fmoc-L-Dap(Teoc)-OH
CAS Number
1248587-10-1
Purity
≥ 98 % (dosage par titration, HPLC)
Molecular Formula
C24H30N2O6Si
Molecular Weight
470.6
MDL Number
MFCD27952850
PubChem ID
75294314
Appearance
Poudre blanc cassé
Optical Rotation
[a] D 20 = -20 ± 1 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Dap(Teoc)-OH
CAS Number
1248587-10-1
Purity
≥ 98 % (dosage par titration, HPLC)
Molecular Formula
C24H30N2O6Si
Molecular Weight
470.6
MDL Number
MFCD27952850
PubChem ID
75294314
Appearance
Poudre blanc cassé
Optical Rotation
[a] D 20 = -20 ± 1 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Na-Fmoc-Nb-trimethylsilylethoxycarbonyl-L-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly in creating peptide-based drugs that require specific amino acid sequences for efficacy.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutic applications.
  • Research in Neuroscience: It is utilized in studies related to neuropeptides, helping researchers explore the role of specific peptides in neurological functions and disorders.
  • Material Science: The compound can be employed in the development of novel materials, particularly those that require specific chemical properties for applications in sensors or drug delivery systems.

Citations