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Catalog Number:
31878
Fmoc-L-Agb(Pbf,Boc)-OH
Purity:
≥ 99,7 % (HPLC chirale)
Synonym(s):
Acide 2-(Fmoc-amino)-4-(N-Pbf, N'-Boc-guanidino)-L-butyrique, Fmoc-Nar(Pbf,Boc)-OH
Temperature Sensitive
Documents
$93.14 /100 mg
Taille
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Product Information

Fmoc-L-Agb(Pbf,Boc)-OH is a versatile amino acid derivative widely used in peptide synthesis and drug development. This compound features a unique combination of protective groups, including Fmoc (9-fluorenylmethoxycarbonyl), Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl), and Boc (tert-butyloxycarbonyl), which facilitate the selective protection of amino groups during the synthesis process. Its structural characteristics make it an excellent choice for researchers looking to streamline the synthesis of complex peptides, enhancing yield and purity while minimizing side reactions.

In practical applications, Fmoc-L-Agb(Pbf,Boc)-OH is particularly valuable in the pharmaceutical industry for developing peptide-based therapeutics and vaccines. Its stability under various reaction conditions allows for efficient coupling reactions, making it a preferred choice for solid-phase peptide synthesis. Researchers benefit from its compatibility with various coupling reagents and solvents, enabling flexibility in experimental design. This compound not only simplifies the synthesis process but also contributes to the overall efficiency and effectiveness of peptide production.

Synonyms
Acide 2-(Fmoc-amino)-4-(N-Pbf, N'-Boc-guanidino)-L-butyrique, Fmoc-Nar(Pbf,Boc)-OH
Purity
≥ 99,7 % (HPLC chirale)
Molecular Formula
C 38 H 46 N 4 O 9 S
Molecular Weight
734.9
MDL Number
MFCD13184919
Melting Point
> 63 °C (déc.)
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -5,0 à -6,5 ° (C=1 dans MeOH)
Conditions
Conserver à ≤ -4 °C
General Information
Synonyms
Acide 2-(Fmoc-amino)-4-(N-Pbf, N'-Boc-guanidino)-L-butyrique, Fmoc-Nar(Pbf,Boc)-OH
Purity
≥ 99,7 % (HPLC chirale)
Molecular Formula
C 38 H 46 N 4 O 9 S
Molecular Weight
734.9
MDL Number
MFCD13184919
Melting Point
> 63 °C (déc.)
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -5,0 à -6,5 ° (C=1 dans MeOH)
Conditions
Conserver à ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-Agb(Pbf,Boc)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for studying protein interactions and functions.
  • Drug Development: Its application in medicinal chemistry facilitates the design of novel therapeutic agents, particularly in the development of peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes to link biomolecules, enhancing the efficacy of drug delivery systems and improving the targeting of therapies.
  • Research in Cancer Therapeutics: It plays a significant role in developing targeted cancer therapies, where specific peptide sequences can be designed to bind to cancer cells, minimizing side effects on healthy tissues.
  • Protein Engineering: Researchers utilize this compound to modify proteins, enabling the study of protein stability and activity, which is crucial for understanding various biological processes.

Citations