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Catalog Number:
37603
CAS Number:
138112-76-2
Agomélatine
Synonym(s):
N- [2-(7-méthoxy-1-naphtalényl)éthyl]acétamide
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Product Information

Agomelatine is a novel antidepressant that combines the properties of a melatonergic agent and a serotonin receptor antagonist, making it a unique choice for the treatment of major depressive disorder. This compound is particularly notable for its ability to regulate circadian rhythms, which can be beneficial for patients experiencing sleep disturbances associated with depression. Agomelatine's mechanism of action involves the modulation of melatonin receptors, promoting sleep while also enhancing mood, thus addressing both the psychological and physiological aspects of depression.

In clinical settings, Agomelatine has demonstrated efficacy in improving sleep quality and reducing anxiety symptoms, making it a valuable option for healthcare professionals seeking to provide comprehensive treatment for their patients. Its favorable side effect profile compared to traditional antidepressants, such as SSRIs, makes it an attractive alternative for those who may be sensitive to common side effects. Researchers and clinicians can leverage Agomelatine's unique properties to enhance patient outcomes in mental health care.

Synonyms
N- [2-(7-méthoxy-1-naphtalényl)éthyl]acétamide
CAS Number
138112-76-2
Molecular Formula
C 15 H 17 NO 2
Molecular Weight
243.31
MDL Number
MFCD00916659
PubChem ID
82148
Melting Point
106 - 110 °C
Appearance
Poudre cristalline blanche ou presque blanche
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
N- [2-(7-méthoxy-1-naphtalényl)éthyl]acétamide
CAS Number
138112-76-2
Molecular Formula
C 15 H 17 NO 2
Molecular Weight
243.31
MDL Number
MFCD00916659
PubChem ID
82148
Melting Point
106 - 110 °C
Appearance
Poudre cristalline blanche ou presque blanche
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Agomelatine is widely utilized in research focused on:

  • Depression Treatment: Primarily used as an antidepressant, it helps regulate circadian rhythms and improve mood, offering a unique mechanism compared to traditional SSRIs.
  • Sleep Disorders: Its melatonergic properties make it effective in treating sleep disturbances, providing a natural alternative for patients with insomnia.
  • Neuroprotection: Research indicates potential neuroprotective effects, making it a candidate for studies on neurodegenerative diseases like Alzheimer's.
  • Psychiatric Disorders: Agomelatine is being explored for its efficacy in managing anxiety and bipolar disorders, providing a multi-faceted approach to mental health.
  • Combination Therapies: It is often investigated in combination with other medications to enhance therapeutic outcomes in complex psychiatric conditions.

Citations