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Catalog Number:
00393
CAS Number:
7665-99-8
Guanosine-3',5'-cyclic monophosphate
Purity:
≥ 99% (HPLC, UV)
Synonym(s):
3',5'-cGMP
Temperature Sensitive
Documents
$43.87 /5MG
Pack Size Availability Price
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Product Information

Guanosine-3':5'-cyclic monophosphate, commonly referred to as cGMP, is a vital second messenger in various biological processes, playing a crucial role in signal transduction pathways. This compound is integral to the regulation of numerous physiological functions, including vasodilation, neurotransmission, and cellular signaling. Its unique structure allows it to interact with specific proteins and enzymes, facilitating the conversion of extracellular signals into intracellular responses. Researchers utilize cGMP in studies related to cardiovascular health, neurobiology, and cellular metabolism, making it a valuable tool in both academic and pharmaceutical research.

In addition to its role in basic research, Guanosine-3':5'-cyclic monophosphate is also employed in the development of therapeutic agents targeting conditions such as hypertension and erectile dysfunction. Its ability to modulate smooth muscle relaxation and blood flow makes it a key player in cardiovascular therapies. With its diverse applications and significance in biological systems, cGMP continues to be a compound of interest for scientists and industry professionals alike, offering insights into cellular mechanisms and potential pathways for drug development.

Synonyms
3',5'-cGMP
CAS Number
7665-99-8
Purity
≥ 99% (HPLC, UV)
Molecular Formula
C10H12N5O7P
Molecular Weight
345.21
MDL Number
MFCD00070129
PubChem ID
135402012
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
3',5'-cGMP
CAS Number
7665-99-8
Purity
≥ 99% (HPLC, UV)
Molecular Formula
C10H12N5O7P
Molecular Weight
345.21
MDL Number
MFCD00070129
PubChem ID
135402012
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Guanosine-3':5'-cyclic monophosphate is widely utilized in research focused on:

  • Cell Signaling: This compound plays a crucial role in cellular signaling pathways, particularly in the regulation of various physiological processes. Researchers use it to study signal transduction mechanisms in cells.
  • Pharmaceutical Development: It serves as a valuable tool in drug discovery, helping scientists to develop new therapeutics targeting specific diseases, especially those related to the nervous system.
  • Biochemical Research: Its application in studying enzyme activity and regulation allows researchers to explore metabolic pathways, leading to a better understanding of cellular functions.
  • Gene Expression Studies: Guanosine-3':5'-cyclic monophosphate is instrumental in investigating gene expression and regulation, providing insights into how genes are turned on or off in response to various stimuli.
  • Neuroscience: In neuroscience research, it is used to examine neurotransmitter signaling and the effects of cyclic nucleotides on neuronal activity, contributing to advancements in understanding brain function.

Citations