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Catalog Number:
01354
CAS Number:
124655-17-0
Boc-D-α-tert-butylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-α-tert-butyl-Gly-OH, Boc-D-Tle-OH, (R-N-Boc-2-amino-3,3-dimethylbutyric acid
Documents
$29.34 /1G
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Product Information

Boc-D-a-tert-butylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butyl protective group, which enhances its stability and solubility, making it an ideal choice for researchers looking to develop complex peptides with improved bioactivity. Its unique structure allows for the introduction of chirality in peptide chains, which is crucial for the development of biologically active compounds.

In the pharmaceutical industry, Boc-D-a-tert-butylglycine is often employed in the synthesis of peptide-based drugs, particularly those targeting specific receptors or enzymes. Its ability to facilitate the formation of stable peptide bonds while maintaining the integrity of the amino acid sequence makes it a valuable tool in drug discovery and development. Additionally, its favorable properties can lead to improved pharmacokinetics and bioavailability of the resulting peptides, making it an essential component in the formulation of effective therapeutic agents.

Synonyms
Boc-D-α-tert-butyl-Gly-OH, Boc-D-Tle-OH, (R-N-Boc-2-amino-3,3-dimethylbutyric acid
CAS Number
124655-17-0
Purity
≥ 98% (HPLC)
Molecular Formula
C11H21NO4
Molecular Weight
231.3
MDL Number
MFCD00065575
Melting Point
115-120 °C
Appearance
White powder
Optical Rotation
[a]D20 = +2 ± 0.5º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-α-tert-butyl-Gly-OH, Boc-D-Tle-OH, (R-N-Boc-2-amino-3,3-dimethylbutyric acid
CAS Number
124655-17-0
Purity
≥ 98% (HPLC)
Molecular Formula
C11H21NO4
Molecular Weight
231.3
MDL Number
MFCD00065575
Melting Point
115-120 °C
Appearance
White powder
Optical Rotation
[a]D20 = +2 ± 0.5º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-a-tert-butylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its unique structure aids in the design of new drugs, particularly in creating compounds with improved bioavailability and stability. Researchers can leverage its properties to enhance therapeutic efficacy.
  • Bioconjugation: Boc-D-a-tert-butylglycine is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules. This is particularly beneficial in the development of targeted drug delivery systems.
  • Protein Engineering: It plays a role in protein engineering, where it can be incorporated into proteins to study structure-function relationships. This helps in understanding protein interactions and designing better enzymes or antibodies.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for potential applications in neuroprotective agents, aiding in the development of treatments for neurodegenerative diseases.

Citations