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Catalog Number:
04091
CAS Number:
198545-76-5
Fmoc-4-bromo-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Phe(4-Br)-OH, Fmoc-p-bromo-D-Phe-OH
Documents
$39.16 /1G
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Product Information

Fmoc-4-bromo-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of the amino group during the synthesis of peptides. Its bromine substitution at the para position of the phenyl ring enhances its reactivity, making it an excellent choice for introducing specific functionalities into peptide sequences. Researchers and industry professionals appreciate its role in the development of peptide-based therapeutics, where precise modifications can lead to improved bioactivity and selectivity.

In addition to its applications in peptide synthesis, Fmoc-4-bromo-D-phenylalanine serves as a valuable building block in the design of novel biomaterials and drug delivery systems. Its unique properties allow for the incorporation of various functional groups, enabling the creation of tailored peptides with enhanced stability and efficacy. This compound stands out among similar products due to its ease of use and the ability to streamline complex synthetic pathways, making it an essential tool for researchers aiming to innovate in the fields of medicinal chemistry and biochemistry.

Synonyms
Fmoc-D-Phe(4-Br)-OH, Fmoc-p-bromo-D-Phe-OH
CAS Number
198545-76-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.3
MDL Number
MFCD00273459
PubChem ID
4712549
Melting Point
170 - 177 °C
Appearance
White to off-white powder or white amorphous powder
Optical Rotation
[a]20D = 20 - 26 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(4-Br)-OH, Fmoc-p-bromo-D-Phe-OH
CAS Number
198545-76-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.3
MDL Number
MFCD00273459
PubChem ID
4712549
Melting Point
170 - 177 °C
Appearance
White to off-white powder or white amorphous powder
Optical Rotation
[a]20D = 20 - 26 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-bromo-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of specific amino acids into peptide chains.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially in designing peptide-based therapeutics that target specific biological pathways.
  • Bioconjugation: The bromine atom in this compound can be used for bioconjugation reactions, enabling researchers to attach biomolecules to peptides, which is essential for creating targeted drug delivery systems.
  • Protein Engineering: This chemical is utilized in the modification of proteins, enhancing their stability and functionality, which is crucial in biotechnology applications.
  • Research in Neuroscience: It can be used in studies related to neuropeptides, helping researchers understand the role of specific peptides in neurological functions and disorders.

Citations