🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
05021
CAS Number:
169555-95-7
Fmoc-3-(4'-pyridyl)-L-alanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Ala(4'-pyridyl)-OH, Fmoc-β-(4'-pyridyl)-Ala-OH, Fmoc-(S)-2-amino-3-(4'-pyridyl)propanoic acid
Documents
$121.28 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-3-(4'-pyridyl)-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique pyridyl side chain enhances the compound's ability to participate in various chemical reactions, making it a valuable building block for researchers in medicinal chemistry and biochemistry.

In practical applications, Fmoc-3-(4'-pyridyl)-L-alanine is particularly beneficial in the development of peptide-based therapeutics, where its structural properties can influence the biological activity of the resulting peptides. Its stability and compatibility with standard coupling reagents allow for efficient incorporation into peptide sequences, facilitating the exploration of novel therapeutic agents. Researchers appreciate its ability to improve solubility and bioavailability in drug formulations, making it an essential component in the design of effective pharmaceutical compounds.

Synonyms
Fmoc-L-Ala(4'-pyridyl)-OH, Fmoc-β-(4'-pyridyl)-Ala-OH, Fmoc-(S)-2-amino-3-(4'-pyridyl)propanoic acid
CAS Number
169555-95-7
Purity
≥ 98% (HPLC)
Molecular Formula
C23H20N2O4
Molecular Weight
388.4
MDL Number
MFCD00672566
PubChem ID
3882867
Melting Point
198 - 203 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -45 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Ala(4'-pyridyl)-OH, Fmoc-β-(4'-pyridyl)-Ala-OH, Fmoc-(S)-2-amino-3-(4'-pyridyl)propanoic acid
CAS Number
169555-95-7
Purity
≥ 98% (HPLC)
Molecular Formula
C23H20N2O4
Molecular Weight
388.4
MDL Number
MFCD00672566
PubChem ID
3882867
Melting Point
198 - 203 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -45 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-(4'-pyridyl)-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: The unique structure enhances the bioactivity of peptide-based drugs, making it valuable in pharmaceutical research aimed at developing new therapeutics.
  • Bioconjugation: It is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Diagnostics: The compound's properties are leveraged in the design of diagnostic tools, particularly in assays that require specific interactions with biological targets.
  • Material Science: In the field of material science, it is applied in creating functional materials that can respond to environmental stimuli, which is useful in sensors and smart materials.

Citations