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Catalog Number:
07543
CAS Number:
167698-68-2
Z-Leu-Arg-Gly-Gly-AMC·AcOH
Documents
$441.90 /25MG
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Product Information

Z-Leu-Arg-Gly-Gly-AMC·AcOH is a specialized peptide compound that plays a crucial role in biochemical research and pharmaceutical applications. This compound is particularly valued for its utility as a substrate in enzyme assays, especially for proteases and peptidases. Its unique structure allows for the efficient monitoring of enzymatic activity, making it an essential tool for researchers studying enzyme kinetics and inhibition. The incorporation of the AMC (7-amino-4-methylcoumarin) moiety provides a fluorescent signal upon cleavage, enabling sensitive detection and quantification of enzymatic reactions.

In addition to its applications in enzyme studies, Z-Leu-Arg-Gly-Gly-AMC·AcOH is also explored in drug development, particularly in the design of peptide-based therapeutics. Its ability to mimic natural substrates makes it a valuable candidate for developing inhibitors or modulators of specific biological pathways. Researchers can leverage its properties to gain insights into various physiological processes, enhancing the understanding of disease mechanisms and therapeutic targets. This compound stands out for its versatility and effectiveness in both academic and industrial settings, making it a preferred choice for professionals in the life sciences.

CAS Number
167698-68-2
Molecular Formula
C34H44N8O8·C2H4O2
Molecular Weight
752.82
MDL Number
MFCD03788097
PubChem ID
146157544
Conditions
Store at 0-8°C
General Information
CAS Number
167698-68-2
Molecular Formula
C34H44N8O8·C2H4O2
Molecular Weight
752.82
MDL Number
MFCD03788097
PubChem ID
146157544
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-Leu-Arg-Gly-Gly-AMC·AcOH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly for studies involving protein interactions and enzymatic activities.
  • Fluorogenic Assays: It is commonly used in fluorogenic assays to monitor protease activity, providing a sensitive method to detect enzyme function in various biological samples.
  • Drug Development: Researchers leverage its properties in drug discovery processes, particularly in developing inhibitors that target specific proteases linked to diseases.
  • Cellular Studies: The compound is applied in cellular assays to investigate cell signaling pathways, helping scientists understand cellular responses to different stimuli.
  • Biotechnology Applications: It finds use in biotechnological applications, such as the development of biosensors that detect proteolytic activity, which is crucial for monitoring health conditions.

Citations