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Catalog Number:
11963
CAS Number:
173212-86-7
Fmoc-O-methyl-L-homoserine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-HomoSer(Me)-OH
Documents
$100.00 /1G
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Product Information

Fmoc-O-methyl-L-homoserine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances stability but also facilitates the introduction of methoxy groups, making it a valuable building block in the creation of complex peptides and proteins. Researchers in the fields of medicinal chemistry and biochemistry often leverage Fmoc-O-methyl-L-homoserine for its ability to improve the solubility and bioavailability of peptide-based therapeutics.

In addition to its application in peptide synthesis, Fmoc-O-methyl-L-homoserine has shown promise in the development of novel drug candidates targeting various biological pathways. Its compatibility with automated synthesizers allows for high-throughput screening and rapid development of peptide libraries, which are crucial for drug discovery. The compound's favorable properties make it an excellent choice for researchers looking to optimize their synthetic routes while maintaining high yields and purity.

Synonyms
Fmoc-L-HomoSer(Me)-OH
CAS Number
173212-86-7
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO5
Molecular Weight
355.39
MDL Number
MFCD00270543
PubChem ID
63310785
Melting Point
138 - 143 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -28 to -32 º (C=4, in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-HomoSer(Me)-OH
CAS Number
173212-86-7
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO5
Molecular Weight
355.39
MDL Number
MFCD00270543
PubChem ID
63310785
Melting Point
138 - 143 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -28 to -32 º (C=4, in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-methyl-L-homoserine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides.
  • Drug Development: It plays a crucial role in the development of pharmaceuticals, especially in designing peptide-based drugs that can target specific biological pathways effectively.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: It is utilized in studies involving neurotransmitter pathways, contributing to the understanding of neurological disorders and potential therapeutic interventions.
  • Protein Engineering: The compound aids in modifying proteins to enhance their stability and functionality, which is vital for applications in biotechnology and synthetic biology.

Citations