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Catalog Number:
15123
CAS Number:
206060-42-6
Fmoc-3-nitro-L-phenylalanine
Purity:
≥ 99% (Assay)
Synonym(s):
Fmoc-L-Phe(3-NO2)-OH, Fmoc-m-nitro-L-Phe-OH, Fmoc-Phe(3-NO2)-OH
Documents
$83.32 /1G
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Product Information

Fmoc-3-nitro-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis. Its unique nitro group enhances the compound's reactivity and allows for the introduction of specific functionalities, making it an invaluable tool for researchers in medicinal chemistry and biochemistry.

In practical applications, Fmoc-3-nitro-L-phenylalanine is particularly beneficial in the design of peptide-based therapeutics and in the study of protein interactions. Its ability to incorporate into peptides while maintaining stability under various conditions makes it ideal for creating complex structures that can be used in drug discovery and development. Researchers appreciate its compatibility with various coupling reagents and its role in generating peptides with enhanced biological activity.

Synonyms
Fmoc-L-Phe(3-NO2)-OH, Fmoc-m-nitro-L-Phe-OH, Fmoc-Phe(3-NO2)-OH
CAS Number
206060-42-6
Purity
≥ 99% (Assay)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD01317718
PubChem ID
6915693
Appearance
White solid/powder
Optical Rotation
[a]D20 = -36 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(3-NO2)-OH, Fmoc-m-nitro-L-Phe-OH, Fmoc-Phe(3-NO2)-OH
CAS Number
206060-42-6
Purity
≥ 99% (Assay)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD01317718
PubChem ID
6915693
Appearance
White solid/powder
Optical Rotation
[a]D20 = -36 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-nitro-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences for various applications.
  • Drug Development: Its unique properties make it valuable in the design of novel pharmaceuticals, particularly in targeting specific biological pathways, enhancing drug efficacy.
  • Bioconjugation: The chemical is used in bioconjugation techniques to attach biomolecules, such as proteins or antibodies, to other molecules, facilitating targeted drug delivery systems.
  • Fluorescent Probes: Researchers utilize it to develop fluorescent probes for imaging applications, aiding in the visualization of cellular processes in real-time.
  • Research in Neuroscience: Its application in studying neurotransmitter interactions and receptor binding contributes to advancements in understanding neurological disorders.

Citations