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Catalog Number:
15289
CAS Number:
269398-78-9
Fmoc-4-nitro-D-β-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-HomoPhe(4-NO2)-OH, Fmoc-(R-3-amino-4-(4-nitrophenyl)butyric acid
Documents
$79.22 /100MG
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Product Information

Fmoc-4-nitro-D-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a nitro group on the aromatic ring, enhances its reactivity and makes it an ideal candidate for various applications in medicinal chemistry and biochemistry. Researchers often leverage Fmoc-4-nitro-D-b-homophenylalanine in the development of peptide-based therapeutics, where its stability and compatibility with standard coupling reagents are crucial for successful synthesis.

In addition to its role in peptide synthesis, this compound is also valuable in the study of protein interactions and the design of novel biomolecules. Its ability to incorporate into peptide chains allows for the exploration of structure-activity relationships, making it a favored choice among researchers focused on drug discovery and development. The compound's favorable properties, such as its solubility and stability under various conditions, further enhance its utility in laboratory settings, ensuring reliable results in experimental applications.

Synonyms
Fmoc-D-β-HomoPhe(4-NO2)-OH, Fmoc-(R-3-amino-4-(4-nitrophenyl)butyric acid
CAS Number
269398-78-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22N2O6
Molecular Weight
446.46
MDL Number
MFCD01860920
PubChem ID
53229887
Appearance
White powder
Optical Rotation
[a]D25 = +30 ± 2º (C=1% in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-HomoPhe(4-NO2)-OH, Fmoc-(R-3-amino-4-(4-nitrophenyl)butyric acid
CAS Number
269398-78-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22N2O6
Molecular Weight
446.46
MDL Number
MFCD01860920
PubChem ID
53229887
Appearance
White powder
Optical Rotation
[a]D25 = +30 ± 2º (C=1% in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-nitro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure aids in the design of peptide-based drugs, particularly in the development of therapeutics targeting specific diseases, enhancing efficacy and selectivity.
  • Bioconjugation: The nitro group can be used for bioconjugation applications, facilitating the attachment of peptides to various biomolecules, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is valuable in studying neuropeptides, contributing to the understanding of neurological pathways and potential treatments for neurodegenerative diseases.
  • Analytical Chemistry: It is employed as a standard in analytical methods, helping researchers quantify peptide concentrations and assess the purity of synthesized compounds.

Citations