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Catalog Number:
15319
CAS Number:
269726-84-3
Fmoc-3-cyano-D-β-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-HomoPhe(3-CN)-OH, Fmoc-(R)-3-amino-4-(3-cyanophenyl)butyric acid
Documents
$110.70 /100MG
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Product Information

Fmoc-3-cyano-D-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective deprotection of amino acids during solid-phase peptide synthesis. Its structural characteristics, including the cyano group, enhance its reactivity and compatibility with various coupling agents, making it an ideal choice for researchers aiming to create complex peptide sequences.

In the pharmaceutical industry, Fmoc-3-cyano-D-b-homophenylalanine serves as a crucial building block for the development of bioactive peptides and therapeutic agents. Its application extends to the synthesis of peptide-based drugs, where the incorporation of this compound can improve the efficacy and specificity of the resulting molecules. Researchers appreciate its stability and ease of handling, which streamline the synthesis process and contribute to higher yields. With its unique properties and practical applications, Fmoc-3-cyano-D-b-homophenylalanine is an essential tool for professionals in peptide chemistry and drug discovery.

Synonyms
Fmoc-D-β-HomoPhe(3-CN)-OH, Fmoc-(R)-3-amino-4-(3-cyanophenyl)butyric acid
CAS Number
269726-84-3
Purity
≥ 98% (HPLC)
Molecular Formula
C26H22N2O4
Molecular Weight
426.47
MDL Number
MFCD01860979
PubChem ID
53397979
Melting Point
162 - 168 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D25 = 24 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-HomoPhe(3-CN)-OH, Fmoc-(R)-3-amino-4-(3-cyanophenyl)butyric acid
CAS Number
269726-84-3
Purity
≥ 98% (HPLC)
Molecular Formula
C26H22N2O4
Molecular Weight
426.47
MDL Number
MFCD01860979
PubChem ID
53397979
Melting Point
162 - 168 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D25 = 24 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-cyano-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: Its unique structure aids in the development of novel pharmaceuticals, particularly in designing drugs that target specific biological pathways.
  • Bioconjugation: The reactive cyano group facilitates bioconjugation processes, enabling the attachment of biomolecules for targeted drug delivery systems.
  • Research in Neuroscience: It is used to study neuropeptides, contributing to the understanding of neurological functions and potential treatments for disorders.
  • Protein Engineering: The compound's properties allow for modifications in protein structures, enhancing their stability and functionality in various applications.

Citations