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Catalog Number:
15616
CAS Number:
501015-25-4
Fmoc-(S-3-amino-3-(4-nitrophenyl)propionic acid
Synonym(s):
Fmoc-L-β-Phe(4-NO2)-OH, (S-Fmoc-4-nitro-β-phenylalanine
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$206.60 /1G
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Product Information

Fmoc-(S)-3-amino-3-(4-nitrophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, incorporating a 4-nitrophenyl moiety, enhances its application in the development of bioactive peptides and pharmaceuticals. Researchers appreciate its stability and ease of use, making it an ideal choice for solid-phase peptide synthesis (SPPS) and other synthetic methodologies.

In addition to its role in peptide synthesis, Fmoc-(S)-3-amino-3-(4-nitrophenyl)propionic acid can be employed in the design of novel therapeutic agents, particularly in the fields of drug discovery and development. Its ability to facilitate the introduction of specific amino acid sequences allows for the creation of peptides with tailored biological activities. This compound stands out for its potential in advancing research in areas such as cancer therapy and targeted drug delivery, making it a valuable asset for researchers and industry professionals alike.

Synonyms
Fmoc-L-β-Phe(4-NO2)-OH, (S-Fmoc-4-nitro-β-phenylalanine
CAS Number
501015-25-4
Molecular Formula
C24H20N2O6
Molecular Weight
432.43
MDL Number
MFCD03427970
PubChem ID
2759202
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-Phe(4-NO2)-OH, (S-Fmoc-4-nitro-β-phenylalanine
CAS Number
501015-25-4
Molecular Formula
C24H20N2O6
Molecular Weight
432.43
MDL Number
MFCD03427970
PubChem ID
2759202
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(4-nitrophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an essential building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide chains.
  • Drug Development: Researchers use this compound in the design of novel pharmaceuticals, especially in the development of peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The unique structure enables its use in bioconjugation applications, where it can be attached to biomolecules for targeted delivery systems, improving the specificity of drug delivery in cancer therapies.
  • Analytical Chemistry: This chemical is employed in analytical methods, such as HPLC, to separate and analyze peptide mixtures, aiding in quality control and characterization of peptide products.
  • Research in Neuroscience: Its application in synthesizing neuropeptides allows researchers to explore neurological functions and develop potential treatments for neurodegenerative diseases.

Citations