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Catalog Number:
15622
CAS Number:
501015-26-5
Fmoc-(S)-3-amino-3-(2-methylphenyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-Phe(2-Me)-OH, (S)-Fmoc-2-methyl-β-phenylalanine
Documents
$50.30 /100MG
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Product Information

Fmoc-(S)-3-amino-3-(2-methylphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 2-methylphenyl side chain, enhances its applicability in creating complex peptide sequences with improved stability and bioactivity. Researchers and industry professionals appreciate its role in the development of pharmaceuticals, particularly in the design of peptide-based therapeutics and biologically active compounds.

The compound's ability to facilitate the synthesis of peptides with specific functional properties makes it invaluable in medicinal chemistry and biochemistry. Its use in solid-phase peptide synthesis (SPPS) allows for efficient and streamlined production of peptides, which are crucial in various applications, including drug discovery, vaccine development, and the creation of biomolecules for research purposes. With its favorable characteristics, Fmoc-(S)-3-amino-3-(2-methylphenyl)propionic acid stands out as a key reagent for professionals seeking to innovate in peptide chemistry.

Synonyms
Fmoc-L-β-Phe(2-Me)-OH, (S)-Fmoc-2-methyl-β-phenylalanine
CAS Number
501015-26-5
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03427971
PubChem ID
22831633
Melting Point
170 - 172 °C
Appearance
White solid
Optical Rotation
[a]D25 = -8 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Phe(2-Me)-OH, (S)-Fmoc-2-methyl-β-phenylalanine
CAS Number
501015-26-5
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03427971
PubChem ID
22831633
Melting Point
170 - 172 °C
Appearance
White solid
Optical Rotation
[a]D25 = -8 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(2-methylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a crucial role in developing pharmaceuticals, particularly in designing peptide-based drugs that can target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach peptides to various biomolecules, improving the delivery and effectiveness of drugs in targeted therapies.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, helping researchers understand the role of specific amino acids in neurological functions and disorders.
  • Custom Peptide Libraries: This compound is instrumental in creating diverse peptide libraries for screening potential drug candidates, facilitating rapid identification of effective compounds in drug discovery.

Citations