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Catalog Number:
15708
CAS Number:
511272-47-2
Fmoc-(R)-3-amino-3-(1-naphthyl)propionic acid
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-β-Ala-(1-naphthyl)-OH
Documents
$40.00 /100MG
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Product Information

Fmoc-(R)-3-amino-3-(1-naphthyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure, characterized by the presence of a naphthyl group, enhances the stability and solubility of the resulting peptides, making it an ideal choice for researchers focusing on complex peptide sequences.

In practical applications, Fmoc-(R)-3-amino-3-(1-naphthyl)propionic acid is particularly valuable in the pharmaceutical industry for developing novel therapeutics, including peptide-based drugs and biologics. Its ability to facilitate the synthesis of high-purity peptides allows for more efficient drug discovery processes. Additionally, this compound's favorable properties make it suitable for use in various research applications, including studies on protein interactions and enzyme activity. Researchers can benefit from its reliability and effectiveness in producing high-quality peptides, ultimately advancing their projects and contributing to innovative solutions in medicine.

Synonyms
Fmoc-D-β-Ala-(1-naphthyl)-OH
CAS Number
511272-47-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C28H23NO4
Molecular Weight
437.49
MDL Number
MFCD03428028
PubChem ID
2756161
Appearance
White solid
Optical Rotation
[a]D20 = -30 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Ala-(1-naphthyl)-OH
CAS Number
511272-47-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C28H23NO4
Molecular Weight
437.49
MDL Number
MFCD03428028
PubChem ID
2756161
Appearance
White solid
Optical Rotation
[a]D20 = -30 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(1-naphthyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its protective Fmoc group allows for selective deprotection and addition of amino acids.
  • Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, especially in targeting specific biological pathways, enhancing efficacy, and reducing side effects compared to traditional small molecules.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in developing targeted therapies and diagnostics.
  • Research in Neuroscience: Its naphthyl group contributes to studies in neuroscience, where it is employed in the development of compounds that can modulate neurotransmitter systems, potentially leading to new treatments for neurological disorders.
  • Material Science: This chemical is also explored in material science for creating functionalized polymers, which can be used in drug delivery systems or smart materials that respond to environmental stimuli.

Citations