🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
15731
CAS Number:
209252-16-4
Fmoc-D-β-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-HomoPhe-OH, (R-Fmoc-3-amino-4-phenylbutyric acid
Documents
$79.22 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-D-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, known for its protective Fmoc (9-fluorenylmethyloxycarbonyl) group, facilitates the efficient assembly of peptides by providing a stable and easily removable protective group. Its unique structure, characterized by the presence of a phenyl group, enhances the hydrophobic interactions in peptide chains, making it particularly valuable in the design of bioactive peptides and pharmaceuticals. Researchers and industry professionals appreciate its role in solid-phase peptide synthesis, where it contributes to the formation of complex peptide structures with improved stability and bioactivity.

The practical applications of Fmoc-D-b-homophenylalanine extend to various fields, including medicinal chemistry, biotechnology, and materials science. It is commonly employed in the development of peptide-based therapeutics, where its ability to enhance peptide stability and efficacy is crucial. Additionally, its use in combinatorial chemistry allows for the rapid generation of peptide libraries, facilitating drug discovery and development. With its favorable properties and broad applicability, Fmoc-D-b-homophenylalanine stands out as a key building block for researchers aiming to innovate in peptide synthesis and therapeutic design.

Synonyms
Fmoc-D-β-HomoPhe-OH, (R-Fmoc-3-amino-4-phenylbutyric acid
CAS Number
209252-16-4
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD04117843
PubChem ID
4547493
Appearance
White powder
Optical Rotation
[a]D25 = +23.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-HomoPhe-OH, (R-Fmoc-3-amino-4-phenylbutyric acid
CAS Number
209252-16-4
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD04117843
PubChem ID
4547493
Appearance
White powder
Optical Rotation
[a]D25 = +23.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), enhancing the efficiency and yield of desired peptide sequences.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing novel therapeutic peptides, which can lead to more effective treatments for various diseases.
  • Bioconjugation: Fmoc-D-b-homophenylalanine is used in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Protein Engineering: This compound aids in the design of modified proteins with enhanced properties, such as stability and activity, which are essential in biotechnology applications.
  • Research in Neuroscience: It is utilized in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.

Citations