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Catalog Number:
16540
CAS Number:
203866-18-6
Boc-trans-4-fluoro-L-proline methyl ester
Purity:
≥ 99% (Chiral purity, GC)
Synonym(s):
Boc-trans-4-fluoro-L-Pro-OMe, (2S,4R)-Boc-4-fluoropyrrolidine-2-dicarboxylic acid methyl ester
Documents
$34.85 /1G
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Product Information

Boc-trans-4-fluoro-L-proline methyl ester is a valuable compound widely utilized in the synthesis of peptide-based pharmaceuticals and research applications. This compound features a unique fluorine substitution that enhances its biological activity, making it an essential building block in the development of novel therapeutics. Its tert-butyl and methyl ester groups provide stability and solubility, facilitating ease of handling in laboratory settings. Researchers often leverage this compound for its role in the design of inhibitors and modulators in various biological pathways, particularly in the fields of medicinal chemistry and drug discovery.

The versatility of Boc-trans-4-fluoro-L-proline methyl ester extends to its application in the synthesis of complex peptides, where it serves as a chiral auxiliary. This characteristic allows for the selective formation of desired stereoisomers, which is crucial in the development of effective drugs with minimal side effects. Additionally, its compatibility with various coupling reagents makes it an attractive option for chemists looking to streamline their synthetic processes. Overall, this compound stands out for its practical applications in advancing pharmaceutical research and development.

Synonyms
Boc-trans-4-fluoro-L-Pro-OMe, (2S,4R)-Boc-4-fluoropyrrolidine-2-dicarboxylic acid methyl ester
CAS Number
203866-18-6
Purity
≥ 99% (Chiral purity, GC)
Molecular Formula
C11H18FNO4
Molecular Weight
247.26
MDL Number
MFCD07367993
PubChem ID
11608471
Appearance
White to brown solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-trans-4-fluoro-L-Pro-OMe, (2S,4R)-Boc-4-fluoropyrrolidine-2-dicarboxylic acid methyl ester
CAS Number
203866-18-6
Purity
≥ 99% (Chiral purity, GC)
Molecular Formula
C11H18FNO4
Molecular Weight
247.26
MDL Number
MFCD07367993
PubChem ID
11608471
Appearance
White to brown solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-trans-4-fluoro-L-proline methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals targeting specific biological pathways.
  • Drug Development: Its unique structural properties make it valuable in the design of novel drugs, especially in the field of neuropharmacology where it can influence receptor interactions.
  • Bioconjugation: The compound is used in bioconjugation processes to attach biomolecules to drugs, enhancing their efficacy and targeting capabilities in therapeutic applications.
  • Research in Medicinal Chemistry: It plays a significant role in medicinal chemistry research, aiding scientists in understanding the effects of fluorinated amino acids on biological systems.
  • Material Science: The compound is explored for its potential in developing new materials with specific properties, such as increased stability and reactivity, useful in various industrial applications.

Citations