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Catalog Number:
16863
CAS Number:
1217729-44-6
Fmoc-2-(Boc-aminomethyl)-D-phenylalanine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Phe(2-CH2NHBoc)-OH, Fmoc-2-(Boc-aminomethyl)-D-Phe-OH
Documents
$50.30 /100MG
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Product Information

Fmoc-2-(Boc-aminomethyl)-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, specifically the Fmoc and Boc groups, which facilitate the selective modification of amino acids during solid-phase peptide synthesis (SPPS). Its structure allows for enhanced stability and solubility, making it an ideal choice for researchers looking to optimize their peptide synthesis processes.

In practical applications, Fmoc-2-(Boc-aminomethyl)-D-phenylalanine is particularly valuable in the development of therapeutic peptides and complex biomolecules. Its ability to provide a robust scaffold for further modifications enables the creation of peptides with improved bioactivity and specificity. Additionally, this compound is recognized for its compatibility with various coupling reagents, streamlining the synthesis workflow. Researchers and industry professionals can leverage this compound to enhance their peptide libraries and accelerate drug discovery efforts, making it a crucial tool in modern medicinal chemistry.

Synonyms
Fmoc-D-Phe(2-CH2NHBoc)-OH, Fmoc-2-(Boc-aminomethyl)-D-Phe-OH
CAS Number
1217729-44-6
Purity
≥ 97% (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659139
PubChem ID
53398426
Melting Point
118 - 124 °C (Lit.)
Appearance
White powder
Optical Rotation
[a]D25 = 32 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(2-CH2NHBoc)-OH, Fmoc-2-(Boc-aminomethyl)-D-Phe-OH
CAS Number
1217729-44-6
Purity
≥ 97% (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659139
PubChem ID
53398426
Melting Point
118 - 124 °C (Lit.)
Appearance
White powder
Optical Rotation
[a]D25 = 32 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-(Boc-aminomethyl)-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly in targeting specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of peptides to various biomolecules, which is crucial in developing targeted therapies and diagnostics.
  • Research in Neuroscience: It has applications in neuroscience for studying receptor interactions, helping researchers understand neurological pathways and potential treatments for disorders.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to the specific needs of researchers and industries looking for tailored solutions in their projects.

Citations