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Catalog Number:
23163
CAS Number:
152305-87-8
sulfo-NHS-acetate
Purity:
≥ 98% (NMR)
Synonym(s):
Sulfosuccinimidyl acetate
Documents
$154.93 /100MG
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Product Information

Sulfo-NHS-acetate is a versatile chemical compound widely utilized in bioconjugation and protein labeling applications. This sulfonated derivative of N-hydroxysuccinimide (NHS) features a unique acetyl group that enhances its reactivity and solubility in aqueous environments, making it an ideal choice for researchers in the fields of biochemistry and molecular biology. Its ability to form stable amide bonds with primary amines allows for efficient conjugation of biomolecules, such as proteins, peptides, and nucleic acids, facilitating the development of targeted therapeutics and diagnostic tools.

Researchers appreciate sulfo-NHS-acetate for its specificity and efficiency in labeling applications, particularly in the creation of antibody-drug conjugates and fluorescent probes. Its sulfonate group not only improves solubility but also minimizes non-specific binding, ensuring cleaner results in assays and experiments. With its proven track record in enhancing the performance of bioconjugates, sulfo-NHS-acetate stands out as a valuable reagent for advancing scientific research and innovation.

Synonyms
Sulfosuccinimidyl acetate
CAS Number
152305-87-8
Purity
≥ 98% (NMR)
Molecular Formula
C6H6NO7SNa
Molecular Weight
259.17
MDL Number
MFCD01861959
PubChem ID
127857
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Sulfosuccinimidyl acetate
CAS Number
152305-87-8
Purity
≥ 98% (NMR)
Molecular Formula
C6H6NO7SNa
Molecular Weight
259.17
MDL Number
MFCD01861959
PubChem ID
127857
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

sulfo-NHS-acetate is widely utilized in research focused on:

  • Bioconjugation: This compound is ideal for attaching biomolecules such as proteins and antibodies to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Development: It plays a crucial role in modifying drug molecules to improve their solubility and stability, which is essential in pharmaceutical formulations.
  • Protein Labeling: Researchers use sulfo-NHS-acetate for labeling proteins in various assays, allowing for easier detection and quantification in studies related to cell biology and biochemistry.
  • Diagnostic Applications: Its ability to form stable conjugates makes it valuable in creating reagents for immunoassays, which are widely used in clinical diagnostics.
  • Research in Therapeutics: The compound is beneficial in the development of novel therapeutic agents by facilitating the modification of biologically active molecules, leading to improved efficacy and reduced side effects.

Citations