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Catalog Number:
24444
CAS Number:
27607-77-8
Trimethylsilyl trifluoromethanesulfonate
Purity:
≥ 98% (Assay by titration)
Synonym(s):
Trimethylsilyl triflate
Hazmat
Documents
$20.00 /25G
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Product Information

Trimethylsilyl trifluoromethanesulfonate is a versatile reagent widely utilized in organic synthesis and chemical research. This compound serves as an effective silylating agent, enhancing the stability and reactivity of various functional groups, particularly alcohols and amines. Its unique trifluoromethanesulfonate moiety provides exceptional electrophilic properties, making it an ideal choice for facilitating reactions such as nucleophilic substitutions and the formation of silyl ethers. Researchers appreciate its ability to streamline complex synthetic pathways, thereby improving yields and reducing reaction times.

In addition to its role in organic synthesis, Trimethylsilyl trifluoromethanesulfonate is also employed in the development of advanced materials and pharmaceuticals. Its compatibility with a wide range of solvents and substrates allows for its application in diverse fields, including polymer chemistry and medicinal chemistry. The compound's stability under various conditions further enhances its appeal, making it a reliable choice for both laboratory and industrial applications. With its proven track record and broad utility, Trimethylsilyl trifluoromethanesulfonate is an essential tool for chemists seeking to innovate and optimize their processes.

Synonyms
Trimethylsilyl triflate
CAS Number
27607-77-8
Purity
≥ 98% (Assay by titration)
Molecular Formula
C4H9F3O3SSi
Molecular Weight
222.26
MDL Number
MFCD00000406
PubChem ID
65367
Density
1.19 - 1.24 g/mL at 25 °C
Appearance
Clear, colorless to slight yellow liquid
Boiling Point
134 - 144 °C
Refractive Index
n20/D 1.36 (Lit.)
Conditions
Store at RT
General Information
Synonyms
Trimethylsilyl triflate
CAS Number
27607-77-8
Purity
≥ 98% (Assay by titration)
Molecular Formula
C4H9F3O3SSi
Molecular Weight
222.26
MDL Number
MFCD00000406
PubChem ID
65367
Density
1.19 - 1.24 g/mL at 25 °C
Appearance
Clear, colorless to slight yellow liquid
Boiling Point
134 - 144 °C
Refractive Index
n20/D 1.36 (Lit.)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trimethylsilyl trifluoromethanesulfonate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as an effective reagent for the protection of alcohols and amines, allowing chemists to manipulate functional groups without unwanted reactions.
  • Fluorination Reactions: It is used in the introduction of fluorine into organic molecules, which is crucial for developing pharmaceuticals and agrochemicals with enhanced biological activity.
  • Analytical Chemistry: The compound acts as a derivatizing agent in gas chromatography, improving the volatility and detectability of polar compounds in complex mixtures.
  • Silicon Chemistry: It plays a significant role in the synthesis of silyl ethers, which are important intermediates in the production of silicone materials and other organosilicon compounds.
  • Material Science: Its unique properties make it valuable in the development of advanced materials, including coatings and adhesives that require high thermal stability and chemical resistance.

Citations