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Catalog Number:
27967
CAS Number:
66966-09-4
4-Methylumbelliferyl α-L-iduronide
Purity:
≥ 97%
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Product Information

4-Methylumbelliferyl a-L-iduronide is a specialized glycoside that serves as a valuable substrate in biochemical research, particularly in the study of glycosaminoglycan metabolism. This compound is recognized for its role in enzymatic assays, where it acts as a fluorogenic substrate for iduronidase, facilitating the detection of enzyme activity through fluorescence. Its unique structure, featuring a 4-methylumbelliferone moiety, allows for sensitive and specific measurements, making it an essential tool in the fields of biochemistry and molecular biology.

Researchers utilize 4-Methylumbelliferyl a-L-iduronide in various applications, including the investigation of lysosomal storage disorders and the development of therapeutic strategies. Its ability to provide clear, quantifiable results enhances its appeal in diagnostic assays and enzyme activity studies. The compound's stability and ease of use further contribute to its desirability in laboratory settings, enabling scientists to obtain reliable data efficiently. With its significant role in advancing our understanding of enzyme functions and metabolic pathways, 4-Methylumbelliferyl a-L-iduronide is an indispensable asset for professionals in the life sciences.

CAS Number
66966-09-4
Purity
≥ 97%
Molecular Formula
C16H16O9
Molecular Weight
352.29
MDL Number
MFCD00135894
PubChem ID
3683393
Appearance
White to off-white powder
Conditions
Store at 0-8°C
General Information
CAS Number
66966-09-4
Purity
≥ 97%
Molecular Formula
C16H16O9
Molecular Weight
352.29
MDL Number
MFCD00135894
PubChem ID
3683393
Appearance
White to off-white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methylumbelliferyl a-L-iduronide is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate for specific enzymes, allowing researchers to measure enzyme activity in biological samples. Its fluorescent properties enhance detection sensitivity, making it ideal for studying metabolic pathways.
  • Biochemical Research: It is commonly used in studies related to glycosaminoglycan metabolism, particularly in understanding disorders like mucopolysaccharidoses. This helps in developing targeted therapies and diagnostics.
  • Cellular Studies: The compound can be employed in cell culture experiments to investigate cellular uptake and metabolism of glycosaminoglycans, providing insights into cellular functions and disease mechanisms.
  • Drug Development: In pharmaceutical research, it aids in screening potential drug candidates that target specific enzymes involved in glycosaminoglycan degradation, facilitating the development of new treatments.
  • Diagnostic Applications: Its use in diagnostic assays helps identify enzyme deficiencies in patients, enabling early diagnosis and management of related genetic disorders.

Citations