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Catalog Number:
29541
CAS Number:
865-47-4
Potassium tert-butoxide solution 1.0 M in THF
Purity:
≥ 99% (Assay)
Synonym(s):
Potassium tert-butylate solution
Hazmat
Documents
$18.53 /25ML
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Product Information

Potassium tert-butoxide solution, 1.0 M in THF, is a highly effective and versatile reagent widely utilized in organic synthesis. This strong base is known for its ability to deprotonate a variety of substrates, making it an essential tool for chemists in the preparation of alkylated products and in the formation of carbon-carbon bonds. Its solubility in tetrahydrofuran (THF) enhances its reactivity and makes it suitable for a range of reactions, including nucleophilic substitutions and eliminations. Researchers and industry professionals appreciate its efficiency in facilitating complex reactions, particularly in the synthesis of pharmaceuticals and fine chemicals.

This compound is particularly advantageous due to its stability and ease of handling compared to other strong bases. Its use in the preparation of tert-butyl esters and ethers showcases its practical applications in both academic and industrial settings. Potassium tert-butoxide solution is also favored for its ability to promote reactions under mild conditions, reducing the risk of side reactions and improving overall yields. Whether you are engaged in research or large-scale production, this reagent offers reliability and effectiveness in your synthetic endeavors.

Synonyms
Potassium tert-butylate solution
CAS Number
865-47-4
Purity
≥ 99% (Assay)
Molecular Formula
C4H9OK
Molecular Weight
112.21
MDL Number
MFCD00012162
PubChem ID
23665647
Density
0.902 g/mL at 25 °C
Appearance
Colorless to yellowish brown liquid
Conditions
Store at 0-8C
General Information
Synonyms
Potassium tert-butylate solution
CAS Number
865-47-4
Purity
≥ 99% (Assay)
Molecular Formula
C4H9OK
Molecular Weight
112.21
MDL Number
MFCD00012162
PubChem ID
23665647
Density
0.902 g/mL at 25 °C
Appearance
Colorless to yellowish brown liquid
Conditions
Store at 0-8C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Potassium tert-butoxide solution, 1.0 M in THF is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a strong base in various organic reactions, facilitating the deprotonation of weak acids and enabling the formation of carbon-carbon bonds.
  • Grignard Reactions: It is often used in the preparation of Grignard reagents, which are crucial for synthesizing complex organic molecules in pharmaceuticals and agrochemicals.
  • Polymer Chemistry: In polymer science, it acts as a catalyst in the polymerization processes, helping to create high-performance materials with tailored properties.
  • Research Laboratories: Its use in laboratories allows for efficient and reproducible reactions, making it a preferred choice for chemists working on innovative compounds.
  • Environmental Applications: The compound can also play a role in developing environmentally friendly processes, such as green chemistry initiatives that minimize waste and energy consumption.

Citations