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Catalog Number:
29710
CAS Number:
1227750-73-3
Fmoc-L-β-methylisoleucine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-α-tert-amylglycine
Documents
$208.31 /100MG
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Product Information

Fmoc-L-b-methylisoleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, characterized by its fluorenylmethoxycarbonyl (Fmoc) protecting group, enhances the stability and solubility of peptides during synthesis, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure allows for efficient coupling reactions, facilitating the formation of complex peptides that are crucial for therapeutic applications, including the development of peptide-based drugs and vaccines.

Researchers appreciate Fmoc-L-b-methylisoleucine for its ability to improve the yield and purity of synthesized peptides, which is vital for ensuring the efficacy of pharmaceutical compounds. Its application extends to the synthesis of cyclic peptides and peptidomimetics, offering innovative solutions in drug design. Additionally, its compatibility with various coupling reagents and methods makes it a preferred choice for peptide chemists looking to streamline their workflows while achieving high-quality results.

Synonyms
Fmoc-L-α-tert-amylglycine
CAS Number
1227750-73-3
Purity
≥ 99% (HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.44
MDL Number
MFCD18782848
PubChem ID
126673652
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -19 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-α-tert-amylglycine
CAS Number
1227750-73-3
Purity
≥ 99% (HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.44
MDL Number
MFCD18782848
PubChem ID
126673652
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -19 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-methylisoleucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new therapeutic peptides, which can lead to innovative treatments for various diseases.
  • Bioconjugation: Used in bioconjugation techniques, it helps in attaching peptides to other molecules, enhancing the efficacy of drug delivery systems and improving targeting in cancer therapies.
  • Research in Protein Engineering: The compound is instrumental in modifying proteins to study their functions, enabling researchers to explore new biological pathways and mechanisms.
  • Academic Research: It serves as a vital reagent in academic laboratories for studies involving amino acid derivatives, contributing to the advancement of knowledge in organic and medicinal chemistry.

Citations