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Catalog Number:
30800
CAS Number:
10416-59-8
N,O-Bis(trimethylsilyl)acetamide
Purity:
≥ 98% (GC)
Synonym(s):
BSA
Hazmat
Documents
$30.20 /25G
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Product Information

N,O-Bis(trimethylsilyl)acetamide is a versatile reagent widely utilized in organic synthesis and analytical chemistry. This compound serves as an effective silylating agent, enhancing the stability and volatility of various functional groups, making it invaluable for the derivatization of alcohols, amines, and carboxylic acids. Its unique ability to form stable silyl derivatives allows for improved detection and quantification in gas chromatography and mass spectrometry applications. Researchers appreciate its efficiency in facilitating reactions that require mild conditions, thus preserving sensitive functional groups.

In addition to its role in synthesis, N,O-Bis(trimethylsilyl)acetamide is also employed in the preparation of silyl ethers and amides, which are crucial intermediates in the production of pharmaceuticals and agrochemicals. Its compatibility with a wide range of substrates and ease of use make it a preferred choice among chemists looking to streamline their workflows. With its robust performance and reliability, this compound stands out as an essential tool for both academic research and industrial applications.

Synonyms
BSA
CAS Number
10416-59-8
Purity
≥ 98% (GC)
Molecular Formula
C8H21NOSi2
Molecular Weight
203.43
MDL Number
MFCD00008270
PubChem ID
25248
Density
0.832 g/mL at 20 °C
Appearance
Colorless transparent liquid
Conditions
Store at RT
General Information
Synonyms
BSA
CAS Number
10416-59-8
Purity
≥ 98% (GC)
Molecular Formula
C8H21NOSi2
Molecular Weight
203.43
MDL Number
MFCD00008270
PubChem ID
25248
Density
0.832 g/mL at 20 °C
Appearance
Colorless transparent liquid
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N,O-Bis(trimethylsilyl)acetamide is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent for the protection of amines and carboxylic acids, facilitating smoother reactions in organic synthesis.
  • Analytical Chemistry: It is commonly used in derivatization processes for gas chromatography, improving the detection and analysis of various compounds.
  • Pharmaceutical Development: The compound aids in the synthesis of pharmaceutical intermediates, enhancing the efficiency of drug development processes.
  • Silicon-based Materials: It plays a crucial role in the preparation of silicon-containing polymers and materials, which are essential in electronics and coatings.
  • Research Applications: Researchers utilize it in various studies involving silylation reactions, which can lead to improved yields and selectivity in chemical transformations.

Citations