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Catalog Number:
31953
CAS Number:
371770-32-0
Fmoc-L-cyclopentylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-(S)-3-Cyclopentylalanine, Fmoc-Ala(cyclopentyl)-OH
Documents
$60.40 /100MG
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Product Information

Fmoc-L-cyclopentylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a cyclopentyl side chain, which enhances the hydrophobic character of peptides, making it particularly useful in the design of bioactive molecules. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide sequences while providing stability during synthesis. Researchers and industry professionals appreciate its role in creating peptides with improved binding affinities and biological activities, especially in the fields of medicinal chemistry and biochemistry.

The unique structure of Fmoc-L-cyclopentylalanine not only facilitates the synthesis of complex peptides but also contributes to the development of novel therapeutics. Its applications extend to the creation of peptide-based drugs, where the cyclopentyl moiety can enhance pharmacokinetic properties. This compound is ideal for those looking to explore innovative peptide designs with tailored functionalities, making it a crucial component in advancing research and development in various pharmaceutical applications.

Synonyms
Fmoc-(S)-3-Cyclopentylalanine, Fmoc-Ala(cyclopentyl)-OH
CAS Number
371770-32-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C23H25NO4
Molecular Weight
379.45
MDL Number
MFCD03094886
PubChem ID
4049341
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -17 ± 2 ° (C=1 in DMF) [a]D20 = -8 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-(S)-3-Cyclopentylalanine, Fmoc-Ala(cyclopentyl)-OH
CAS Number
371770-32-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C23H25NO4
Molecular Weight
379.45
MDL Number
MFCD03094886
PubChem ID
4049341
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -17 ± 2 ° (C=1 in DMF) [a]D20 = -8 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-cyclopentylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), enhancing the efficiency and yield of complex peptide chains.
  • Drug Development: Its unique cyclopentyl side chain can improve the pharmacological properties of peptide-based drugs, making them more effective in targeting specific biological pathways.
  • Bioconjugation: Fmoc-L-cyclopentylalanine is used in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted therapies and diagnostics.
  • Research in Protein Engineering: This compound aids in the design of novel proteins with enhanced stability and activity, providing researchers with tools to explore protein function and interactions.
  • Material Science: Its properties can be leveraged in the development of new materials, particularly in creating polymers that require specific interactions or functionalities, broadening the scope of applications in nanotechnology and materials engineering.

Citations