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Catalog Number:
31970
CAS Number:
212688-54-5
Fmoc-D-β-homoleucine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-β-HomoLeu-OH, (R-3-(Fmoc-amino)-5-methyl-hexanoic acid
Documents
$93.14 /100MG
Pack Size Availability Price
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Product Information

Fmoc-D-b-homoleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure enhances stability and solubility, making it an ideal choice for researchers focusing on complex peptide sequences. Fmoc-D-b-homoleucine is particularly valuable in the pharmaceutical industry for the development of therapeutic peptides, where precise amino acid incorporation is essential for bioactivity.

In addition to its applications in peptide synthesis, Fmoc-D-b-homoleucine can also be employed in the study of protein interactions and structure-function relationships. Its ability to facilitate the formation of stable peptide bonds allows for the exploration of novel peptide-based therapeutics. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-D-β-HomoLeu-OH, (R-3-(Fmoc-amino)-5-methyl-hexanoic acid
CAS Number
212688-54-5
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.45
MDL Number
MFCD06202394
PubChem ID
4532729
Appearance
White solid
Optical Rotation
[a]20D = 10 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-β-HomoLeu-OH, (R-3-(Fmoc-amino)-5-methyl-hexanoic acid
CAS Number
212688-54-5
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.45
MDL Number
MFCD06202394
PubChem ID
4532729
Appearance
White solid
Optical Rotation
[a]20D = 10 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-b-homoleucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and diverse peptide sequences.
  • Drug Development: It plays a crucial role in the development of pharmaceuticals, especially in designing peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: Fmoc-D-b-homoleucine is used in bioconjugation techniques, enabling the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Protein Engineering: This compound aids in the modification of proteins, facilitating the study of protein structure and function, which is vital for understanding diseases and developing new treatments.
  • Academic Research: It is extensively used in academic laboratories for various studies related to peptide chemistry, providing researchers with a reliable tool for exploring new chemical reactions and methodologies.

Citations