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Catalog Number:
37212
CAS Number:
433-06-7
2,2,2-Trifluoroethyl p-toluenesulfonate
Purity:
≥ 99% (Assay by titration, GC)
Synonym(s):
p-Toluenesulfonic acid 2,2,2-trifluoroethyl ester
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$18.53 /25G
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Product Information

2,2,2-Trifluoroethyl p-toluenesulfonate is a versatile chemical compound known for its unique trifluoromethyl group, which enhances its reactivity and solubility in various organic solvents. This compound is widely utilized in the synthesis of pharmaceuticals and agrochemicals, where it serves as an effective electrophilic reagent in nucleophilic substitution reactions. Its ability to introduce trifluoroethyl groups into target molecules makes it invaluable in the development of novel compounds with improved biological activity and stability. Researchers appreciate its role in facilitating complex organic transformations, particularly in the fields of medicinal chemistry and materials science.

In addition to its synthetic applications, 2,2,2-Trifluoroethyl p-toluenesulfonate is also recognized for its potential in the production of fluorinated polymers and specialty chemicals. Its unique properties allow for the fine-tuning of molecular characteristics, making it a preferred choice for developing advanced materials with specific performance attributes. With its growing significance in various research and industrial applications, this compound stands out as a key player in the ongoing quest for innovative solutions in chemistry.

Synonyms
p-Toluenesulfonic acid 2,2,2-trifluoroethyl ester
CAS Number
433-06-7
Purity
≥ 99% (Assay by titration, GC)
Molecular Formula
C9H9F3O3S
Molecular Weight
254.22
MDL Number
MFCD00000443
PubChem ID
67942
Melting Point
36 - 38 °C
Appearance
White to off-white powder
Boiling Point
104 °C/0.8 mmHg
Conditions
Store at RT
General Information
Synonyms
p-Toluenesulfonic acid 2,2,2-trifluoroethyl ester
CAS Number
433-06-7
Purity
≥ 99% (Assay by titration, GC)
Molecular Formula
C9H9F3O3S
Molecular Weight
254.22
MDL Number
MFCD00000443
PubChem ID
67942
Melting Point
36 - 38 °C
Appearance
White to off-white powder
Boiling Point
104 °C/0.8 mmHg
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,2,2-Trifluoroethyl p-toluenesulfonate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, facilitating the introduction of trifluoroethyl groups into various substrates, which can enhance the properties of pharmaceuticals and agrochemicals.
  • Fluorinated Compounds Development: It plays a crucial role in the synthesis of fluorinated compounds, which are important in the development of advanced materials and specialty chemicals, offering improved stability and performance.
  • Drug Discovery: In medicinal chemistry, it is used to modify drug candidates, potentially improving their efficacy and bioavailability, thus aiding in the creation of more effective therapeutics.
  • Polymer Chemistry: The compound is utilized in the production of fluorinated polymers, which exhibit unique properties such as chemical resistance and thermal stability, making them suitable for high-performance applications.
  • Analytical Chemistry: It is employed as a derivatizing agent in analytical methods, enhancing the detection and quantification of various analytes, which is essential for quality control in pharmaceuticals and environmental testing.

Citations