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Catalog Number:
37456
CAS Number:
51805-45-9
Tris-(carboxyethyl)phosphine hydrochloride  
Grade:
Molecular Biology Grade
Purity:
≥ 98% (HPLC)
Synonym(s):
TCEP·HCl
Hazmat
Documents
$43.87 /1G
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Product Information

Tris-(carboxyethyl)phosphine hydrochloride is a versatile phosphine derivative known for its strong reducing properties, making it an essential reagent in various chemical reactions. This compound is particularly valued in organic synthesis and biochemistry, where it serves as a reducing agent for disulfides and other oxidized species. Its ability to stabilize reactive intermediates enhances its utility in the synthesis of complex organic molecules, including pharmaceuticals and fine chemicals. Researchers often utilize Tris-(carboxyethyl)phosphine hydrochloride in the preparation of peptide and protein conjugates, where it effectively reduces disulfide bonds, facilitating the formation of desired structures.

Additionally, this compound is recognized for its water solubility, which allows for easy handling and incorporation into aqueous reaction systems. Its unique properties make it a preferred choice over other phosphine reagents, particularly in applications requiring mild reaction conditions and high selectivity. With its broad range of applications in synthetic organic chemistry and bioconjugation, Tris-(carboxyethyl)phosphine hydrochloride is an invaluable tool for researchers and industry professionals seeking efficient and effective solutions in their work.

Synonyms
TCEP·HCl
CAS Number
51805-45-9
Purity
≥ 98% (HPLC)
Grade
Molecular Biology Grade
Molecular Formula
C9H15O6P·HCl
Molecular Weight
286.6
MDL Number
MFCD00145469
PubChem ID
2734570
Melting Point
176 - 186 °C
Appearance
White crystalline powder, or white crysta
Conditions
Store at 0 - 8 °C under Nitrogen
General Information
Synonyms
TCEP·HCl
CAS Number
51805-45-9
Purity
≥ 98% (HPLC)
Grade
Molecular Biology Grade
Molecular Formula
C9H15O6P·HCl
Molecular Weight
286.6
MDL Number
MFCD00145469
PubChem ID
2734570
Melting Point
176 - 186 °C
Appearance
White crystalline powder, or white crysta
Conditions
Store at 0 - 8 °C under Nitrogen
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tris-(carboxyethyl)phosphine hydrochloride is widely utilized in research focused on:

  • Biochemistry and Molecular Biology: This compound serves as a reducing agent, effectively stabilizing proteins and enzymes during purification processes, which is crucial for maintaining their functional integrity.
  • Pharmaceutical Development: It plays a significant role in drug formulation, particularly in the synthesis of phosphine derivatives that can enhance drug efficacy and bioavailability.
  • Analytical Chemistry: Used in various analytical techniques, it aids in the detection and quantification of metal ions, providing a reliable method for environmental monitoring and quality control.
  • Polymer Science: The compound is employed in the development of specialty polymers, contributing to improved material properties such as flexibility and resistance to degradation.
  • Nanotechnology: It is utilized in the synthesis of nanoparticles, where its reducing properties facilitate the formation of stable nanostructures with potential applications in electronics and medicine.

Citations