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Catalog Number:
37602
CAS Number:
147403-03-0
Azilsartan
Purity:
≥ 98% (HPLC)
Synonym(s):
1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl) [1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid
Documents
$201.60 /200MG
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Product Information

Azilsartan is a potent angiotensin II receptor antagonist, primarily utilized in the management of hypertension. This compound works by selectively blocking the action of angiotensin II, a hormone that constricts blood vessels, thereby promoting vasodilation and lowering blood pressure. Azilsartan is recognized for its long-lasting effects, making it a preferred choice for patients requiring sustained blood pressure control. Its unique structure allows for enhanced receptor binding, which can lead to improved therapeutic outcomes compared to other antihypertensive agents.

In clinical settings, Azilsartan has demonstrated efficacy in reducing cardiovascular risks associated with high blood pressure, making it a valuable option for healthcare professionals. Its application extends beyond hypertension management, as ongoing research explores its potential benefits in heart failure and chronic kidney disease. With its favorable safety profile and effectiveness, Azilsartan stands out as a reliable choice for both patients and healthcare providers seeking effective blood pressure management solutions.

Synonyms
1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl) [1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid
CAS Number
147403-03-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H20N4O5
Molecular Weight
456.46
MDL Number
MFCD00916395
PubChem ID
135415867
Melting Point
188 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl) [1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid
CAS Number
147403-03-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H20N4O5
Molecular Weight
456.46
MDL Number
MFCD00916395
PubChem ID
135415867
Melting Point
188 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Azilsartan is widely utilized in research focused on:

  • Hypertension Treatment: This compound is primarily used in the pharmaceutical industry for managing high blood pressure. It works by blocking specific receptors, leading to effective blood pressure reduction.
  • Cardiovascular Health Studies: Researchers study Azilsartan to understand its long-term effects on heart health, particularly in patients with hypertension and related cardiovascular conditions.
  • Combination Therapies: Azilsartan is often investigated in combination with other antihypertensive agents, providing insights into synergistic effects that enhance overall treatment efficacy.
  • Clinical Trials: It plays a vital role in clinical trials aimed at evaluating new treatment protocols for hypertension, helping to establish safety and effectiveness profiles.
  • Pharmacokinetics Research: The compound is studied for its absorption, distribution, metabolism, and excretion characteristics, which are crucial for developing optimized dosing regimens.

Citations