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Catalog Number:
37619
CAS Number:
125995-03-1
Atorvastatin lactone
Purity:
≥ 95% (HPLC)
Synonym(s):
5-(4-Fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide, Atorvastatin related compound H
Documents
$126.39 /25MG
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Product Information

Atorvastatin lactone is a potent compound widely recognized for its role in cholesterol management and cardiovascular health. As a lactone derivative of atorvastatin, it exhibits significant efficacy in inhibiting HMG-CoA reductase, an enzyme critical in the biosynthesis of cholesterol. This property makes atorvastatin lactone a valuable asset in pharmaceutical formulations aimed at treating hyperlipidemia and preventing cardiovascular diseases. Its unique structure enhances its bioavailability and therapeutic potential, positioning it as a preferred choice for researchers and healthcare professionals focused on lipid regulation.

In addition to its primary application in cholesterol-lowering therapies, atorvastatin lactone has shown promise in various research settings, including studies on metabolic disorders and inflammation. Its ability to modulate lipid profiles while offering anti-inflammatory benefits makes it a versatile compound for developing innovative treatments. Researchers can leverage atorvastatin lactone's unique properties to explore new therapeutic avenues, making it an essential addition to any laboratory or pharmaceutical development program.

Synonyms
5-(4-Fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide, Atorvastatin related compound H
CAS Number
125995-03-1
Purity
≥ 95% (HPLC)
Molecular Formula
C33H33FN2O4
Molecular Weight
540.64
MDL Number
MFCD00899262
PubChem ID
13923664
Melting Point
161 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-(4-Fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide, Atorvastatin related compound H
CAS Number
125995-03-1
Purity
≥ 95% (HPLC)
Molecular Formula
C33H33FN2O4
Molecular Weight
540.64
MDL Number
MFCD00899262
PubChem ID
13923664
Melting Point
161 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Atorvastatin lactone is widely utilized in research focused on:

  • Cardiovascular Health: This compound is primarily known for its role in lowering cholesterol levels, making it crucial in the development of medications for heart disease and stroke prevention.
  • Pharmaceutical Development: Researchers use atorvastatin lactone to explore new formulations and delivery methods, enhancing the effectiveness of cholesterol-lowering therapies.
  • Metabolic Studies: It is employed in studies examining lipid metabolism and the effects of statins on metabolic syndrome, providing insights into broader health implications.
  • Drug Interaction Research: The compound serves as a model in pharmacokinetic studies to understand how atorvastatin interacts with other medications, aiding in safe prescribing practices.
  • Biochemical Pathway Analysis: Atorvastatin lactone is used to investigate the biochemical pathways involved in cholesterol synthesis and regulation, contributing to advancements in personalized medicine.

Citations