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Catalog Number:
37645
CAS Number:
1134-47-0
Baclofen
Purity:
≥ 98% (Assay by titration)
Synonym(s):
4-Amino-3-(4-chlorophenyl)butyric acid, Lioresal
Hazmat
Documents
$29.34 /1G
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Product Information

Baclofen is a potent muscle relaxant and antispastic agent, primarily used in the treatment of spasticity resulting from conditions such as multiple sclerosis and spinal cord injuries. This compound acts as a GABA-B receptor agonist, effectively reducing muscle tone and alleviating involuntary muscle contractions. Its unique mechanism of action not only provides relief from muscle stiffness but also enhances the quality of life for patients suffering from debilitating neuromuscular disorders. Baclofen is also being explored for its potential in treating chronic pain and alcohol dependence, showcasing its versatility in therapeutic applications.

In the pharmaceutical industry, Baclofen is valued for its efficacy and safety profile, making it a preferred choice for healthcare professionals. Its ability to penetrate the blood-brain barrier allows for effective central nervous system action, which is crucial for managing symptoms associated with neurological disorders. Researchers are continuously investigating new formulations and delivery methods to optimize its therapeutic benefits, further expanding its potential applications in modern medicine.

Synonyms
4-Amino-3-(4-chlorophenyl)butyric acid, Lioresal
CAS Number
1134-47-0
Purity
≥ 98% (Assay by titration)
Molecular Formula
C10H12ClNO2
Molecular Weight
213.66
MDL Number
MFCD00055143
PubChem ID
2284
Melting Point
208 °C
Appearance
White to light yellow to light orange powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-Amino-3-(4-chlorophenyl)butyric acid, Lioresal
CAS Number
1134-47-0
Purity
≥ 98% (Assay by titration)
Molecular Formula
C10H12ClNO2
Molecular Weight
213.66
MDL Number
MFCD00055143
PubChem ID
2284
Melting Point
208 °C
Appearance
White to light yellow to light orange powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Baclofen is widely utilized in research focused on:

  • Treatment of Muscle Spasticity: Commonly prescribed for conditions like multiple sclerosis and spinal cord injuries, Baclofen helps reduce muscle stiffness and improve mobility.
  • Management of Chronic Pain: It is used in pain management protocols, particularly for neuropathic pain, providing relief where traditional analgesics may fall short.
  • Alcohol Dependence Therapy: Research indicates Baclofen may assist in reducing cravings and withdrawal symptoms in individuals with alcohol use disorder, offering a potential alternative to conventional treatments.
  • Neurological Research: In laboratory settings, Baclofen is studied for its effects on neurotransmitter systems, contributing to our understanding of various neurological disorders.
  • Veterinary Medicine: Baclofen is also explored for use in animals, particularly for managing spasticity and pain in veterinary patients, showcasing its versatility across species.

Citations