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Catalog Number:
37660
CAS Number:
14919-77-8
Benserazide hydrochloride
Purity:
98.5 - 101.0% (HPLC)
Synonym(s):
DL-Serine 2-(2,3,4-Trihydroxybenzyl)hydrazide hydrochloride
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$25.20 /1G
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Product Information

Benserazide hydrochloride is a vital pharmaceutical compound primarily used as a peripheral decarboxylase inhibitor in the treatment of Parkinson's disease. By inhibiting the enzyme aromatic L-amino acid decarboxylase, it effectively enhances the bioavailability of levodopa, a precursor to dopamine, thereby improving therapeutic outcomes for patients. This compound is recognized for its ability to mitigate the side effects associated with levodopa therapy, such as nausea and vomiting, making it an essential component in combination therapies.

In addition to its role in Parkinson's treatment, Benserazide hydrochloride has potential applications in research settings, particularly in studies focused on neurotransmitter regulation and neuropharmacology. Its unique properties allow researchers to explore the intricate dynamics of dopamine synthesis and its implications in various neurological disorders. With its established efficacy and safety profile, Benserazide hydrochloride remains a crucial asset for both clinical and research applications, offering significant benefits in enhancing patient care and advancing scientific understanding.

Synonyms
DL-Serine 2-(2,3,4-Trihydroxybenzyl)hydrazide hydrochloride
CAS Number
14919-77-8
Purity
98.5 - 101.0% (HPLC)
Molecular Formula
C10H15N3O5·HCl
Molecular Weight
293.7
MDL Number
MFCD00078571
PubChem ID
26964
Melting Point
180 °C (dec.)
Appearance
Almost white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
DL-Serine 2-(2,3,4-Trihydroxybenzyl)hydrazide hydrochloride
CAS Number
14919-77-8
Purity
98.5 - 101.0% (HPLC)
Molecular Formula
C10H15N3O5·HCl
Molecular Weight
293.7
MDL Number
MFCD00078571
PubChem ID
26964
Melting Point
180 °C (dec.)
Appearance
Almost white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Benserazide hydrochloride is widely utilized in research focused on:

  • Parkinson's Disease Treatment: This compound is primarily used in combination with levodopa to enhance the effectiveness of Parkinson's disease therapies by inhibiting the peripheral metabolism of levodopa, allowing more of it to reach the brain.
  • Pharmaceutical Development: Researchers often incorporate benserazide in drug formulations aimed at improving the pharmacokinetics of other medications, particularly in neurological disorders, thus optimizing therapeutic outcomes.
  • Animal Studies: In preclinical research, benserazide is used in animal models to study the progression of Parkinson's disease and evaluate new treatment strategies, providing insights into disease mechanisms and potential interventions.
  • Neuropharmacology Research: This compound serves as a valuable tool in neuropharmacology studies, helping scientists understand the interactions between neurotransmitters and the effects of dopaminergic drugs.
  • Formulation Science: Benserazide hydrochloride is also explored in formulation science for its role in stabilizing active pharmaceutical ingredients, ensuring the efficacy and safety of medications.

Citations