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Catalog Number:
37689
CAS Number:
91599-74-5
Benidipine hydrochloride
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
3-[(3RS)-1-Benzylpiperidin-3-yl] 5-methyl (4RS)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, KW‐3049
Hazmat
Temperature Sensitive
Documents
$205.61 /100MG
Pack Size Availability Price
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Product Information

Benidipine hydrochloride is a potent calcium channel blocker primarily utilized in the management of hypertension and angina pectoris. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced heart workload. Its unique structure, featuring a benzylpiperidine moiety, enhances its selectivity and efficacy, making it a preferred choice in clinical settings for patients requiring effective blood pressure control.

In addition to its cardiovascular applications, Benidipine hydrochloride has shown promise in research related to neuroprotection and potential anti-inflammatory effects, expanding its relevance in therapeutic areas beyond traditional cardiovascular treatment. Researchers and healthcare professionals appreciate its favorable pharmacokinetic profile, which allows for once-daily dosing, improving patient compliance. With its established safety and efficacy, Benidipine hydrochloride continues to be a valuable asset in both clinical and research environments.

Synonyms
3-[(3RS)-1-Benzylpiperidin-3-yl] 5-methyl (4RS)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, KW‐3049
CAS Number
91599-74-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C28H31N3O6·HCl
Molecular Weight
542.03
MDL Number
MFCD00906929
PubChem ID
123768
Melting Point
200 °C
Appearance
Light yellow to yellow to orange powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
3-[(3RS)-1-Benzylpiperidin-3-yl] 5-methyl (4RS)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, KW‐3049
CAS Number
91599-74-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C28H31N3O6·HCl
Molecular Weight
542.03
MDL Number
MFCD00906929
PubChem ID
123768
Melting Point
200 °C
Appearance
Light yellow to yellow to orange powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Benidipine hydrochloride is widely utilized in research focused on:

  • Cardiovascular Health: This compound is primarily used as an antihypertensive agent, helping to manage high blood pressure effectively. Its unique mechanism allows for better control of blood pressure compared to other medications, making it a preferred choice for many healthcare professionals.
  • Pharmaceutical Development: Researchers are exploring its potential in developing new formulations and combination therapies for hypertension and related cardiovascular diseases, enhancing treatment options for patients.
  • Clinical Studies: It is often included in clinical trials to assess its efficacy and safety, contributing valuable data that can lead to improved treatment protocols for managing hypertension.
  • Drug Interaction Research: The compound is studied for its interactions with other medications, providing insights that can help in creating safer and more effective treatment regimens for patients with multiple health conditions.
  • Patient Compliance Improvement: Due to its favorable side effect profile, benidipine hydrochloride can enhance patient adherence to treatment plans, which is crucial for long-term management of chronic conditions like hypertension.

Citations