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Catalog Number:
37728
CAS Number:
61422-45-5
Carmofur
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
5-Fluoro-1-hexylcarbamoyluracil, HCFU
Hazmat
Documents
$75.00 /1G
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Product Information

Carmofur is a fluorinated pyrimidine derivative known for its unique properties and applications in the pharmaceutical industry. This compound is recognized for its potential as an antitumor agent, particularly in the treatment of various cancers. Its mechanism of action involves the inhibition of thymidylate synthase, which is crucial for DNA synthesis, making it a valuable asset in cancer therapy. Researchers have explored Carmofur's effectiveness in combination therapies, enhancing the efficacy of other chemotherapeutic agents. Additionally, its ability to penetrate biological membranes allows for improved bioavailability, making it a promising candidate for further development in targeted cancer treatments.

In the realm of research, Carmofur's distinct chemical structure offers opportunities for the synthesis of novel derivatives with enhanced therapeutic profiles. Its applications extend beyond oncology, with potential uses in antiviral and antibacterial formulations. The compound's stability and solubility characteristics further support its versatility in various formulations, appealing to both researchers and industry professionals seeking innovative solutions in drug development.

Synonyms
5-Fluoro-1-hexylcarbamoyluracil, HCFU
CAS Number
61422-45-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C11H16FN3O3
Molecular Weight
257.27
MDL Number
MFCD00866284
PubChem ID
2577
Melting Point
112 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Fluoro-1-hexylcarbamoyluracil, HCFU
CAS Number
61422-45-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C11H16FN3O3
Molecular Weight
257.27
MDL Number
MFCD00866284
PubChem ID
2577
Melting Point
112 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Carmofur is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily known for its role as an antitumor agent, particularly in the treatment of colorectal cancer. Its ability to inhibit tumor growth makes it a valuable option in oncology.
  • Pharmaceutical Development: Carmofur serves as a lead compound in the development of new anticancer drugs. Researchers are exploring its derivatives to enhance efficacy and reduce side effects, contributing to innovative therapies.
  • Combination Therapies: It is often used in combination with other chemotherapeutic agents to improve treatment outcomes. This synergistic approach can lead to more effective cancer management strategies.
  • Research on Drug Resistance: Carmofur is employed in studies investigating mechanisms of drug resistance in cancer cells, helping scientists understand how to overcome challenges in treatment.
  • Targeted Drug Delivery Systems: Its unique properties make it a candidate for incorporation into novel drug delivery systems, enhancing the precision of cancer therapies and minimizing damage to healthy tissues.

Citations