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Catalog Number:
37804
CAS Number:
77883-43-3
Doxazosin mesylate
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(1,4-benzodioxan-2-yl)carbonyl]piperazine methanesulfonate, Doxazosin methanesulfonate
Documents
$70.91 /100MG
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Product Information

Doxazosin mesylate is a potent alpha-1 adrenergic antagonist primarily used in the treatment of hypertension and benign prostatic hyperplasia (BPH). This compound works by relaxing blood vessels, which helps to lower blood pressure, and it also alleviates urinary symptoms associated with BPH by relaxing the muscles in the prostate and bladder neck. Its unique structure, featuring a piperazine ring and a methanesulfonic acid moiety, enhances its solubility and bioavailability, making it a preferred choice in clinical settings.

In addition to its therapeutic applications, Doxazosin mesylate is also utilized in research settings to study adrenergic receptor interactions and their physiological effects. Its effectiveness in managing symptoms of BPH and hypertension, coupled with its favorable pharmacokinetic profile, positions it as a valuable compound for both healthcare professionals and researchers. The compound's ability to improve patient quality of life while minimizing side effects makes it a significant player in the pharmaceutical landscape.

Synonyms
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(1,4-benzodioxan-2-yl)carbonyl]piperazine methanesulfonate, Doxazosin methanesulfonate
CAS Number
77883-43-3
Purity
≥ 98% (HPLC)
Molecular Formula
C23H25N5O5·CH4O3S
Molecular Weight
547.58
MDL Number
MFCD00216023
PubChem ID
62978
Melting Point
269 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(1,4-benzodioxan-2-yl)carbonyl]piperazine methanesulfonate, Doxazosin methanesulfonate
CAS Number
77883-43-3
Purity
≥ 98% (HPLC)
Molecular Formula
C23H25N5O5·CH4O3S
Molecular Weight
547.58
MDL Number
MFCD00216023
PubChem ID
62978
Melting Point
269 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Doxazosin mesylate is widely utilized in research focused on:

  • Hypertension Treatment: Commonly prescribed for managing high blood pressure, it helps relax blood vessels, improving blood flow and reducing heart strain.
  • BPH Management: Effective in treating benign prostatic hyperplasia, it alleviates urinary symptoms by relaxing muscles in the prostate and bladder neck.
  • Research on Cardiovascular Health: Used in studies investigating its effects on cardiovascular function, providing insights into heart health and blood pressure regulation.
  • Pharmacological Studies: Serves as a model compound in drug development research, helping scientists understand receptor interactions and drug efficacy.
  • Combination Therapies: Often explored in conjunction with other medications to enhance therapeutic outcomes in patients with complex health issues.

Citations