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Catalog Number:
37886
CAS Number:
105628-07-7
Fasudil hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride, 5-(1-Homopiperazinyl)sulfonylisoquinoline hydrochloride
Temperature Sensitive
Documents
$130.60 /100MG
Pack Size Availability Price
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Product Information

Fasudil hydrochloride is a potent and selective Rho-kinase inhibitor, widely recognized for its therapeutic applications in various medical fields. This compound has shown significant promise in the treatment of cerebral vasospasm following subarachnoid hemorrhage, making it a valuable asset in neurology. Additionally, its ability to enhance blood flow and reduce vascular resistance positions it as a potential candidate for treating conditions such as pulmonary hypertension and ischemic heart disease. Researchers are also exploring its neuroprotective properties, which could lead to advancements in therapies for neurodegenerative diseases.

With its unique mechanism of action, Fasudil hydrochloride stands out among similar compounds, offering a targeted approach to modulating vascular tone and improving microcirculation. Its versatility in application, combined with a favorable safety profile, makes it an attractive option for both clinical and research settings. As the medical community continues to investigate its full potential, Fasudil hydrochloride remains at the forefront of innovative treatments aimed at improving patient outcomes in various vascular-related conditions.

Synonyms
1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride, 5-(1-Homopiperazinyl)sulfonylisoquinoline hydrochloride
CAS Number
105628-07-7
Purity
≥ 98% (HPLC)
Molecular Formula
C14H17N3O2S·HCl
Molecular Weight
327.83
MDL Number
MFCD00943198
PubChem ID
163751
Melting Point
222 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
General Information
Synonyms
1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride, 5-(1-Homopiperazinyl)sulfonylisoquinoline hydrochloride
CAS Number
105628-07-7
Purity
≥ 98% (HPLC)
Molecular Formula
C14H17N3O2S·HCl
Molecular Weight
327.83
MDL Number
MFCD00943198
PubChem ID
163751
Melting Point
222 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fasudil hydrochloride is widely utilized in research focused on various therapeutic applications. Here are five practical applications:

  • Stroke Treatment: This compound is primarily used in the treatment of cerebral vasospasm following subarachnoid hemorrhage, helping to improve blood flow and reduce neurological damage.
  • Neuroprotection: Researchers explore its potential in protecting neurons from damage in conditions like Alzheimer's and Parkinson's disease, making it a valuable candidate in neurodegenerative research.
  • Cardiovascular Health: It is investigated for its ability to improve endothelial function and reduce hypertension, offering a promising avenue for cardiovascular therapies.
  • Anti-Fibrotic Properties: Fasudil hydrochloride shows potential in treating fibrosis in various organs, including the lungs and liver, which is crucial for developing therapies for fibrotic diseases.
  • Cancer Research: Its role in inhibiting tumor growth and metastasis is being studied, providing insights into new cancer treatment strategies.

These applications highlight its versatility and importance in advancing medical research and therapeutic development.

Citations